{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:03:12Z","timestamp":1756339392441,"version":"3.44.0"},"reference-count":11,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bmj.com\/company\/legal-information\/terms-conditions\/legal-information\/tdm-licencepolicy"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2018,9,3]]},"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:p>Precocious puberty is characterised by premature appearance of secondary sexual characteristics before the age of 7 years in girls and 9 years in boys. Dandy-Walker malformation comprises a spectrum of intracranial malformations of the posterior fossa. We present a case of a 7-year-old male child who has presented with features of central precocious puberty and on further evaluation has been found to have Dandy-Walker variant and secondary hypothyroidism. The following case report describes this association which is extremely rare and has never been described in literature.<\/jats:p>","DOI":"10.1136\/bcr-2018-226281","type":"journal-article","created":{"date-parts":[[2018,12,18]],"date-time":"2018-12-18T17:19:47Z","timestamp":1545153587000},"page":"e226281","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Dandy-Walker variant with precocious puberty: a rare association"],"prefix":"10.1136","volume":"11","author":[{"given":"Rajesh","family":"Rajput","sequence":"first","affiliation":[{"name":"Department of Endocrinology and Medicine Unit, Pt. B D Sharma Postgraduate Institute of Medical Sciences, Rohtak, Haryana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanat","family":"Mishra","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Medicine Unit, Pt. B D Sharma Postgraduate Institute of Medical Sciences, Rohtak, Haryana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parul","family":"Ahlawat","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Medicine Unit, Pt. B D Sharma Postgraduate Institute of Medical Sciences, Rohtak, Haryana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pawan Kumar","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Medicine, Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,11,28]]},"reference":[{"key":"2025082701163695000_11.1.e226281.1","unstructured":"Styne DM , Grumbach MM . et al Puberty: Ontogeny, Neuroendocrinology, Physiology, and Disorders . In: Melmed S , Polonsky KS , Larsen PR , Kronenberg HM , . 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Association with the Dandy-Walker syndrome and dysraphic anomalies]","volume":"16","author":"Bach","year":"1969","journal-title":"Ann Pediatr"},{"key":"2025082701163695000_11.1.e226281.11","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1007\/s12098-009-0130-1","article-title":"Dandy-Walker\u2019s variant and tetralogy of fallot with atrial septal defect and patent ductus arteriosus and primary hypothyroidy\u2013a new association","volume":"76","author":"Ozdemir","year":"2009","journal-title":"Indian J Pediatr"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/data.bmj.org\/tdm\/10.1136\/bcr-2018-226281","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-226281","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T08:16:45Z","timestamp":1756282605000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-226281"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2018,11,28]]},"published-print":{"date-parts":[[2018,11]]}},"alternative-id":["10.1136\/bcr-2018-226281"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-226281","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2018,11]]}}}