{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T03:37:24Z","timestamp":1787888244553,"version":"build-2784847793"},"reference-count":13,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,5,21]]},"published-print":{"date-parts":[[2019,6,3]]},"abstract":"<jats:p>Type 1 neurofibromatosis (NF1) is a hereditary disorder with an incidence of approximately 1:3000 at birth. Gastrointestinal (GI) lesions occur in approximately one-third of the patients, with most being asymptomatic and diagnosed incidentally. Symptomatic lesions leading to GI bleeding are uncommon. We share our experience of an elderly man with NF1, who presented with massive recurrent GI bleeding secondary to jejunal neurofibromas. The lesions were identified on CT scan of abdomen, and the patient was managed with resection of the involved bowel segment.<\/jats:p>","DOI":"10.1136\/bcr-2018-226303","type":"journal-article","created":{"date-parts":[[2019,6,4]],"date-time":"2019-06-04T06:36:32Z","timestamp":1559630192000},"page":"e226303","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Recurrent gastrointestinal bleeding in a patient with type 1 neurofibromatosis"],"prefix":"10.1136","volume":"12","author":[{"given":"Vidhyachandra","family":"Gandhi","sequence":"first","affiliation":[{"name":"Gastrointestinal and HPB Surgery, Ruby Hall Clinic, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pratik","family":"Gautam","sequence":"additional","affiliation":[{"name":"Gastrointestinal and HPB Surgery, Ruby Hall Clinic, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taher","family":"Chharchhodawala","sequence":"additional","affiliation":[{"name":"Histopatholgy, Ruby Hall Clinic, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nitin","family":"Pai","sequence":"additional","affiliation":[{"name":"Medical Gastroenterology, Ruby Hall Clinic, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2019,6,3]]},"reference":[{"key":"2025082710330521000_12.6.e226303.1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(07)70075-3"},{"key":"2025082710330521000_12.6.e226303.2","unstructured":"Friedman JM , Riccardi VM . Neurofibromatosis: phenotype, natural history and pathogenesis. 3rd ed. Baltimore: Md Johns Hopkins University Press 1999."},{"key":"2025082710330521000_12.6.e226303.3","doi-asserted-by":"publisher","DOI":"10.1080\/00365520310005712"},{"key":"2025082710330521000_12.6.e226303.4","first-page":"852","article-title":"Gastrointestinal manifestations of neurofibromatosis type 1 (Recklinghausen\u2019s disease): clinicopathological spectrum with pathogenetic considerations","volume":"5","author":"Agaimy","year":"2012","journal-title":"Int J Clin Exp Pathol"},{"key":"2025082710330521000_12.6.e226303.5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1991.tb00888.x"},{"key":"2025082710330521000_12.6.e226303.6","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)13166-2"},{"key":"2025082710330521000_12.6.e226303.7","doi-asserted-by":"crossref","first-page":"5573","DOI":"10.3748\/wjg.v11.i35.5573","article-title":"Solitary colonic neurofibroma in a patient with transient segmental colitis: case report","volume":"11","author":"Panteris","year":"2005","journal-title":"World J Gastroenterol"},{"key":"2025082710330521000_12.6.e226303.8","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2006.045906"},{"key":"2025082710330521000_12.6.e226303.9","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-009-0940-5"},{"key":"2025082710330521000_12.6.e226303.10","doi-asserted-by":"publisher","DOI":"10.1148\/rg.252045176"},{"key":"2025082710330521000_12.6.e226303.11","doi-asserted-by":"crossref","first-page":"80","DOI":"10.4103\/1319-3767.39623","article-title":"Intra-abdominal manifestations of von Recklinghausen\u2019s neurofibromatosis","volume":"14","author":"Rastogi","year":"2008","journal-title":"Saudi J Gastroenterol"},{"key":"2025082710330521000_12.6.e226303.12","doi-asserted-by":"crossref","first-page":"137","DOI":"10.3904\/kjim.1992.7.2.137","article-title":"Intestinal neurofibromatosis in von Recklinghausen\u2019s disease: presenting as chronic anemia due to recurrent intestinal hemorrhage","volume":"7","author":"Hahn","year":"1992","journal-title":"Korean J Intern Med"},{"key":"2025082710330521000_12.6.e226303.13","first-page":"1","article-title":"Rezvan Zardarib Small Bowel Obstruction Due to Gastrointestinal Neurofibromas and Lipomas","volume":"5","author":"Guldfeldt","year":"2014","journal-title":"J Med Cases"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-226303","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T17:33:17Z","timestamp":1756315997000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-226303"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,3]]},"references-count":13,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2019,6,3]]},"published-print":{"date-parts":[[2019,6,3]]}},"alternative-id":["10.1136\/bcr-2018-226303"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-226303","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,3]]}}}