{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T23:33:53Z","timestamp":1788305633751,"version":"build-2803163510"},"reference-count":11,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,3,20]]},"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:p>Varicella gangrenosum is a gangrenous ulceration of varicella lesions involving the skin and soft tissues of the body. The term was coined more than 100 years ago. This occurs due to superimposed bacterial infection. The presentation of primary varicella in adults is more severe with catastrophic systemic complications as compared with children. These complications include necrotising fasciitis, disseminated intravascular coagulation, wet\/dry gangrene and death, as was seen in our case. Survival is dependent on early diagnosis and treatment. Adequate antibiotic treatment and particularly early radical surgical debridement should be the cornerstone of management. Less than 10 such cases are reported in the literature.<\/jats:p>","DOI":"10.1136\/bcr-2018-226363","type":"journal-article","created":{"date-parts":[[2019,4,4]],"date-time":"2019-04-04T19:27:01Z","timestamp":1554406021000},"page":"e226363","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Varicella gangrenosum in adult: a fatal chickenpox complication"],"prefix":"10.1136","volume":"12","author":[{"given":"Ashish","family":"Sharma","sequence":"first","affiliation":[{"name":"Urology, King George\u2019s Medical University, Lucknow, Uttar-Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1390-6488","authenticated-orcid":false,"given":"Samarth","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Urology, King George\u2019s Medical University, Lucknow, Uttar-Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anamika","family":"Sharma","sequence":"additional","affiliation":[{"name":"Intensive Care, All India Institute of Medical Sciences, New Delhi, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manoj","family":"Kumar","sequence":"additional","affiliation":[{"name":"Urology, King George\u2019s Medical University, Lucknow, Uttar-Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2019,4,4]]},"reference":[{"key":"2025082708512555000_12.4.e226363.1","doi-asserted-by":"crossref","first-page":"924-5","DOI":"10.1097\/00006534-198905000-00044","article-title":"Life-threatening varicella gangrenosum","volume":"83","author":"Stromberg","year":"1989","journal-title":"Plast Reconstr Surg"},{"key":"2025082708512555000_12.4.e226363.2","doi-asserted-by":"crossref","first-page":"46","DOI":"10.5152\/TurkPediatriArs.2016.1300","article-title":"A case of perineal ecthyma gangrenosum","volume":"51","author":"Akkurt","year":"2016","journal-title":"Turk Pediatri Ars"},{"key":"2025082708512555000_12.4.e226363.3","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1111\/j.1365-2230.2006.02301.x","article-title":"Pyoderma gangrenosum on varicella lesions","volume":"32","author":"Mehta","year":"2007","journal-title":"Clin Exp Dermatol"},{"key":"2025082708512555000_12.4.e226363.4","first-page":"656","article-title":"Necrotising soft tissue infections as a complication of chickenpox","volume":"36","author":"Nathan","year":"1995","journal-title":"Singapore Med J"},{"key":"2025082708512555000_12.4.e226363.5","doi-asserted-by":"publisher","DOI":"10.5999\/aps.2012.39.6.673"},{"key":"2025082708512555000_12.4.e226363.6","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.333.7560.181"},{"key":"2025082708512555000_12.4.e226363.7","doi-asserted-by":"publisher","DOI":"10.1136\/adc.63.4.444"},{"issue":"3","key":"2025082708512555000_12.4.e226363.8","doi-asserted-by":"crossref","DOI":"10.1542\/peds.60.3.384a","article-title":"Varieties of varicella gangrenosa","volume":"60","author":"John","year":"1977","journal-title":"Pediatrics"},{"key":"2025082708512555000_12.4.e226363.9","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)81618-X"},{"key":"2025082708512555000_12.4.e226363.10","unstructured":"WHO statement on varicella zoster infections. http:\/\/www.who.int\/wer\/2014\/wer8925.pdf?ua=1."},{"key":"2025082708512555000_12.4.e226363.11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2014\/206152","article-title":"Management of varicella gangrenosa: a life-threatening condition from chickenpox","volume":"2014","author":"Schots","year":"2014","journal-title":"Case Rep Med"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-226363","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T15:51:33Z","timestamp":1756309893000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-226363"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":11,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2019,4,4]]},"published-print":{"date-parts":[[2019,4]]}},"alternative-id":["10.1136\/bcr-2018-226363"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-226363","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4]]}}}