{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T19:06:28Z","timestamp":1778180788008,"version":"3.51.4"},"reference-count":12,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,9,25]]},"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:p>A 59-year-old woman presented to an otolaryngology clinic with an 8-week history of a painless lump over her left parotid gland. Her medical history included an invasive ductal carcinoma (33\u2009mm) and a ductal carcinoma in situ (70\u2009mm) of the right breast, for which she had a mastectomy and various adjuvant therapies. The primary tumour presented 8 years prior to the metachronous metastasis. This patient was a non-smoker and had no significant family history. Post-superficial parotidectomy pathology revealed the parotid gland tumour to be oestrogen receptor-positive and HER2 receptor-positive, thus ruling out the initial differential diagnosis of a pleomorphic adenoma. A consequential total parotidectomy with a posterolateral neck dissection was performed with sparing of the facial nerve. The patient recovered well having only encountered a self-resolving salivary fistula. She portrayed no signs of facial nerve palsy and subsequent imaging scans showed no abnormalities.<\/jats:p>","DOI":"10.1136\/bcr-2018-226494","type":"journal-article","created":{"date-parts":[[2019,10,8]],"date-time":"2019-10-08T14:55:12Z","timestamp":1570546512000},"page":"e226494","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["Reminder of an important clinical lesson: breast cancer metastasis to the parotid gland"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6608-7896","authenticated-orcid":false,"given":"Amisha","family":"Jakharia-Shah","sequence":"first","affiliation":[{"name":"Bristol Medical School, University of Bristol, Bristol, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugh","family":"Wheatley","sequence":"additional","affiliation":[{"name":"ENT Department, Gloucestershire Royal Hospital, Gloucester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Beesley","sequence":"additional","affiliation":[{"name":"Pathology Department, Gloucestershire Royal Hospital, Gloucester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,10,8]]},"reference":[{"key":"2025082709024902000_12.10.e226494.1","first-page":"1","article-title":"Metachronous, single metastasis to the parotid, from primary breast cancer: a case report and review of the literature","volume":"2016","author":"Kmeid","year":"2016","journal-title":"Case Rep Oncol Med"},{"key":"2025082709024902000_12.10.e226494.2","doi-asserted-by":"crossref","unstructured":"Alath P , Kapila K , Hussein S , et al . Parotid gland metastasis of breast cancer diagnosed on fine needle aspiration cytology: case report and review of literature - Cytopathology - Wiley Online Library, 2013.","DOI":"10.1111\/cyt.12108"},{"key":"2025082709024902000_12.10.e226494.3","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.896563"},{"key":"2025082709024902000_12.10.e226494.4","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.44.7805"},{"key":"2025082709024902000_12.10.e226494.5","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6602579"},{"key":"2025082709024902000_12.10.e226494.6","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s10006-009-0146-8","article-title":"Metastatic involvement of parotid from carcinoma of the breast\u2014a case report","volume":"13","author":"Dangore-Khasbage","year":"2009","journal-title":"Oral Maxillofac Surg"},{"key":"2025082709024902000_12.10.e226494.7","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1963.01310170043009"},{"key":"2025082709024902000_12.10.e226494.8","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/S0344-0338(86)80044-9","article-title":"Metastatic tumors to the parotid and submandibular glands: analysis and differential diagnosis of 108 cases","volume":"181","author":"Seifert","year":"1986","journal-title":"Pathology - Research and Practice"},{"key":"2025082709024902000_12.10.e226494.9","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1159\/000335222","article-title":"Parotid gland metastasis of breast cancer: case report and review of the literature","volume":"6","author":"Ando","year":"2011","journal-title":"Breast Care"},{"key":"2025082709024902000_12.10.e226494.10","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1258\/0022215011908649","article-title":"Metachronous bilateral submandibular gland metastases from carcinoma of the breast","volume":"115","author":"Cain","year":"2001","journal-title":"J Laryngol Otol"},{"key":"2025082709024902000_12.10.e226494.11","doi-asserted-by":"crossref","unstructured":"Perez-Fidalgo JA , Chirivella I , Laforga J , et al . Parotid gland metastasis of a breast cancer, 2006.","DOI":"10.1007\/s12094-007-0051-2"},{"key":"2025082709024902000_12.10.e226494.12","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0709(96)90004-6"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-226494","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T16:02:55Z","timestamp":1756310575000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-226494"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":12,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2019,10,8]]},"published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1136\/bcr-2018-226494"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-226494","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10]]}}}