{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:53:20Z","timestamp":1756385600752,"version":"3.44.0"},"reference-count":10,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"accepted":{"date-parts":[[2018,8,22]]},"abstract":"<jats:p>Chondrosarcomas represent a group of malignant tumours composed of cells producing cartilage, and clear cell chondrosarcomas (CCC) represent a variant of these. A rare case of a laryngeal CCC is presented. The patient was a 70-year-old man who presented with a 6-week history of throat pain, worsening dysphonia and a lump in the neck. Examination revealed a level 3 neck mass and positron emission tomography imaging revealed a metabolically active right laryngeal mass. Biopsies revealed a cartilaginous neoplasm. The patient underwent total laryngectomy, and the pathology confirmed CCC of the larynx. Chondrosarcomas are the most common type of sarcoma in the larynx but the CCC variant is rare. CCC are usually low-grade tumours affecting long bones, with a male predominance. Less than six cases have been described in the literature affecting the larynx. Management of these malignancies is complete surgical excision given the high risk of local recurrence.<\/jats:p>","DOI":"10.1136\/bcr-2018-226541","type":"journal-article","created":{"date-parts":[[2018,9,4]],"date-time":"2018-09-04T10:36:07Z","timestamp":1536057367000},"page":"bcr-2018-226541","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Clear cell chondrosarcoma of the larynx"],"prefix":"10.1136","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7676-6171","authenticated-orcid":false,"given":"Thomas","family":"Hendriks","sequence":"first","affiliation":[{"name":"Fiona Stanley Hospital, Murdoch, Western Australia, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe","family":"Cardemil","sequence":"additional","affiliation":[{"name":"Sir Charles Gairdner Hospital, Perth, Western Australia, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chady","family":"Sader","sequence":"additional","affiliation":[{"name":"Fiona Stanley Hospital, Murdoch, Western Australia, Australia"},{"name":"Sir Charles Gairdner Hospital, Perth, Western Australia, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,9,4]]},"reference":[{"key":"2025082722465534000_2018.sep03_1.bcr-2018-226541.1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200207000-00002"},{"key":"2025082722465534000_2018.sep03_1.bcr-2018-226541.2","doi-asserted-by":"publisher","DOI":"10.1097\/00020840-200404000-00008"},{"key":"2025082722465534000_2018.sep03_1.bcr-2018-226541.3","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24618"},{"key":"2025082722465534000_2018.sep03_1.bcr-2018-226541.4","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1080\/000164800750000199","article-title":"Laryngeal chondrosarcoma: a 24-year experience at the royal national throat, nose and ear hospital","volume":"120","author":"Rinaldo","year":"2000","journal-title":"Acta Otolaryngol"},{"key":"2025082722465534000_2018.sep03_1.bcr-2018-226541.5","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200203000-00015"},{"key":"2025082722465534000_2018.sep03_1.bcr-2018-226541.6","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/s00106-004-1089-x","article-title":"[Clear cell chondrosarcoma of the larynx. A rare tumor in an uncommon location]","volume":"53","author":"Kollert","year":"2005","journal-title":"HNO"},{"key":"2025082722465534000_2018.sep03_1.bcr-2018-226541.7","doi-asserted-by":"publisher","DOI":"10.1007\/s003300050897"},{"key":"2025082722465534000_2018.sep03_1.bcr-2018-226541.8","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2001.115858"},{"key":"2025082722465534000_2018.sep03_1.bcr-2018-226541.9","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1758-3284-4-13","article-title":"Clear cell chondrosarcoma of the head and neck","volume":"4","author":"Mokhtari","year":"2012","journal-title":"Head Neck Oncol"},{"key":"2025082722465534000_2018.sep03_1.bcr-2018-226541.10","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/s00402-007-0353-4","article-title":"Clear cell chondrosarcoma of bone: long time follow-up of 18 cases","volume":"128","author":"Donati","year":"2008","journal-title":"Arch Orthop Trauma Surg"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-226541","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T05:47:03Z","timestamp":1756360023000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-226541"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,4]]},"references-count":10,"alternative-id":["10.1136\/bcr-2018-226541"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-226541","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2018,9,4]]}}}