{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T15:42:30Z","timestamp":1772034150742,"version":"3.50.1"},"reference-count":14,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,1,11]]},"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:p>Rectal carcinoma with metastasis to skeletal muscle is a rare finding. According to literature review, 17 cases of skeletal muscle metastasis from colorectal carcinoma have been documented where only six cases were rectal carcinomas.<\/jats:p>\n               <jats:p>We discuss a case of a middle-aged man with a known history of high-grade mucinous adenocarcinoma of the rectum, status post abdominoperineal resection followed by adjuvant radiotherapy and chemotherapy. During the planned chemotherapy course, a right proximal thigh subcutaneous mass was incidentally found which on subsequent biopsy proved to be metastatic from rectal primary site. On subsequent 18F-FDG (Fluorodeoxyglucose) positron emission tomography (PET)\/CT scan after completion of chemotherapy for the purpose of treatment response evaluation, only FDG-avid lesion was residual right proximal thigh metastatic mass without involvement of other common sites, such as liver and lung. In this case, the 18F-FDG-PET\/CT scan was able to exclude additional metastatic sites and also evaluate the patient\u2019s treatment response.<\/jats:p>","DOI":"10.1136\/bcr-2018-226802","type":"journal-article","created":{"date-parts":[[2019,1,23]],"date-time":"2019-01-23T04:55:45Z","timestamp":1548219345000},"page":"e226802","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Rectal adenocarcinoma presenting with thigh muscle metastasis as the only metastatic site"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7183-8992","authenticated-orcid":false,"given":"Abtin","family":"Doroudinia","sequence":"first","affiliation":[{"name":"PET\/CT, Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, The Islamic Republic of Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Payam","family":"Mehrian","sequence":"additional","affiliation":[{"name":"Radiology, Telemedicine Research Center (TRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, The Islamic Republic of Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atosa","family":"Dorudinia","sequence":"additional","affiliation":[{"name":"Pathology, Tracheal Diseases Research Center (TDRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Masih Daneshvari Hospital. Shahid Beheshti University of Medical Sciences, Tehran, The Islamic Republic of Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatemeh","family":"Kaghazchi","sequence":"additional","affiliation":[{"name":"PET\/CT, Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, The Islamic Republic of Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,1,22]]},"reference":[{"key":"2025082707413970000_12.1.e226802.1","doi-asserted-by":"crossref","DOI":"10.1186\/2193-1801-2-399","article-title":"A large thigh mass: a blood clot or a rare skeletal muscle metastasis from renal cell carcinoma","volume":"2","author":"Lohiya","year":"2013","journal-title":"Springerplus"},{"key":"2025082707413970000_12.1.e226802.2","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1097\/MNM.0000000000000368","article-title":"Multiple and solitary skeletal muscle metastases on 18F-FDG PET\/CT imaging","volume":"36","author":"Nocu\u0144","year":"2015","journal-title":"Nucl Med Commun"},{"key":"2025082707413970000_12.1.e226802.3","doi-asserted-by":"publisher","DOI":"10.1102\/1470-7330.2008.0033"},{"key":"2025082707413970000_12.1.e226802.4","doi-asserted-by":"crossref","first-page":"e833","DOI":"10.1097\/MD.0000000000000833","article-title":"Non-hodgkin\u2019s lymphoma of multiple skeletal muscles involvement seen on FDG PET\/CT Scans","volume":"94","author":"Dai","year":"2015","journal-title":"Medicine"},{"key":"2025082707413970000_12.1.e226802.5","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1159\/000218540","article-title":"Painful leg: a very unusual presentation of renal cell carcinoma","volume":"82","author":"G\u00f6zen","year":"2009","journal-title":"Urol Int"},{"key":"2025082707413970000_12.1.e226802.6","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.remn.2015.07.005","article-title":"Uncommon isolated distant subcutaneous tissue and skeletal muscle metastasis from oesophageal cancer diagnosed by 18 F-FDG PET\/CT","volume":"35","author":"Dom\u00ednguez","year":"2016","journal-title":"Revista Espa\u00f1ola de Medicina Nuclear e Imagen Molecular"},{"key":"2025082707413970000_12.1.e226802.7","doi-asserted-by":"publisher","DOI":"10.1097\/RLU.0b013e3182443e32"},{"key":"2025082707413970000_12.1.e226802.8","doi-asserted-by":"publisher","DOI":"10.1097\/01.rlu.0000247784.90704.d7"},{"key":"2025082707413970000_12.1.e226802.9","doi-asserted-by":"crossref","first-page":"214","DOI":"10.4103\/ijnm.IJNM_167_16","article-title":"Rectal carcinoma metastases to multiple skeletal muscles-role of F-18 FDG PET\/CT","volume":"32","author":"Prabhu","year":"2017","journal-title":"Indian J Nucl Med"},{"key":"2025082707413970000_12.1.e226802.10","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21395"},{"key":"2025082707413970000_12.1.e226802.11","doi-asserted-by":"crossref","first-page":"002","DOI":"10.4172\/2161-069X.S12-002","article-title":"Skeletal muscle metastasis secondary to adenocarcinoma of colon: a case report and review of literature","volume":"S12","author":"Tunio","year":"2013","journal-title":"J Gastrointest Dig Syst"},{"key":"2025082707413970000_12.1.e226802.12","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1002\/cncr.23151","article-title":"Metastases to soft tissue: a review of 118 cases over a 30-year period","volume":"112","author":"Plaza","year":"2008","journal-title":"Cancer"},{"key":"2025082707413970000_12.1.e226802.13","first-page":"181","article-title":"Metastatic rectal adenocarcinoma to forearm muscle: An unusual site of metastasis","volume":"35","author":"Unsal","year":"2005","journal-title":"Turkish Journal of Cancer"},{"key":"2025082707413970000_12.1.e226802.14","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-009-1577-1"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-226802","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:41:51Z","timestamp":1756305711000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-226802"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":14,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2019,1,22]]},"published-print":{"date-parts":[[2019,1]]}},"alternative-id":["10.1136\/bcr-2018-226802"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-226802","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1]]}}}