{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T13:34:16Z","timestamp":1789392856612,"version":"build-2803163510"},"reference-count":12,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,1,17]]},"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:p>We describe a woman with both central and peripheral nervous system symptoms consistent with Morvan\u2019s syndrome who was successfully treated with immunosuppression including rituximab and the new antiepileptic drug lacosamide against peripheral nerve hyperexcitability. Despite being over 8\u2009months in hospital and 4\u2009months in an intensive care unit she recovered fully. It is also the first case where cerebrospinal fluid neurofilament-light (NfL) levels were followed during the disease course. The clinical course resembled that of anti-NMDA receptor encephalitis, where patients often recover surprisingly well despite severe symptoms and an extensive time in intensive care. A possible explanation is the comparatively low levels of NfL, indicating disease processes that are not characterised by extensive neuroaxonal degeneration.<\/jats:p>","DOI":"10.1136\/bcr-2018-226832","type":"journal-article","created":{"date-parts":[[2019,2,14]],"date-time":"2019-02-14T05:02:36Z","timestamp":1550120556000},"page":"e226832","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Morvan\u2019s syndrome treated successfully with rituximab and lacosamide"],"prefix":"10.1136","volume":"12","author":[{"given":"Olafur","family":"Sveinsson","sequence":"first","affiliation":[{"name":"Department of Neurology, Karolinska University Hospital, Stockholm, Sweden"},{"name":"Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faiez","family":"Al Nimer","sequence":"additional","affiliation":[{"name":"Department of Neurology, 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