{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,20]],"date-time":"2025-12-20T22:06:55Z","timestamp":1766268415569,"version":"3.44.0"},"reference-count":15,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,2,23]]},"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:p>We present the case of a 14-year-old immune-competent girl with ventriculoperitoneal shunt who was repeatedly hospitalised with meningeal signs despite repeated shunt revision surgeries. Eventually <jats:italic>Mycobacterium fortuitum<\/jats:italic> was isolated and the patient improved after specific treatment. <jats:italic>M. fortuitum<\/jats:italic> is a rapidly growing, non-tuberculous mycobacterium (NTM). NTMs are associated with postsurgical, post-trauma and device-related infections. Most of the present-day surgical equipment, catheters, prostheses and indwelling devices comprised silicone, stainless steel, polyvinyl chloride and polycarbonate, on which NTMs have the tendency to form biofilms. Central nervous system infection caused by NTM carries a high mortality rate (ranging from 35% to 70%), especially in immune-compromised patients. Indwelling device removal along with prolonged treatment with a combination regimen is recommended in such cases.<\/jats:p>","DOI":"10.1136\/bcr-2018-226900","type":"journal-article","created":{"date-parts":[[2019,4,16]],"date-time":"2019-04-16T06:25:30Z","timestamp":1555395930000},"page":"e226900","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["<i>Mycobacterium fortuitum<\/i> as a cause of acute CNS infection in an immune-competent girl undergoing repeated VP shunt surgeries"],"prefix":"10.1136","volume":"12","author":[{"given":"Ashit Bhusan","family":"Xess","sequence":"first","affiliation":[{"name":"Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiran","family":"Bala","sequence":"additional","affiliation":[{"name":"Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aashirwad","family":"Panigrahy","sequence":"additional","affiliation":[{"name":"Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Urvashi","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,4,15]]},"reference":[{"key":"2025082622473971000_12.4.e226900.1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(08)70127-0"},{"key":"2025082622473971000_12.4.e226900.2","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-015-0817-3"},{"key":"2025082622473971000_12.4.e226900.3","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.amjms.2016.02.009","article-title":"Mycobacterium abscessus as a cause of chronic meningitis: a rare clinical Entity","volume":"351","author":"Baidya","year":"2016","journal-title":"Am J Med Sci"},{"key":"2025082622473971000_12.4.e226900.4","doi-asserted-by":"publisher","DOI":"10.3171\/2014.8.PEDS13677"},{"key":"2025082622473971000_12.4.e226900.5","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-199907000-00009"},{"key":"2025082622473971000_12.4.e226900.6","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1227\/00006123-199109000-00028","article-title":"Infection of a shunt by Mycobacterium fortuitum: case report","volume":"29","author":"Chan","year":"1991","journal-title":"Neurosurgery"},{"key":"2025082622473971000_12.4.e226900.7","first-page":"393","article-title":"Ventriculo-peritoneal shunt infection by mycobacterium fortuitum in an adult","volume":"52","author":"Viswanathan","year":"2004","journal-title":"Neurol India"},{"key":"2025082622473971000_12.4.e226900.8","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1111\/j.1525-1403.2008.00181.x","article-title":"Intrathecal drug delivery device infection and meningitis due to Mycobacterium Fortuitum: a case report","volume":"11","author":"Aliabadi","year":"2008","journal-title":"Neuromodulation"},{"key":"2025082622473971000_12.4.e226900.9","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1592\/phco.19.8.661.31530","article-title":"Mycobacterium fortuitum meningitis associated with an epidural catheter: case report and a review of the literature","volume":"19","author":"Madaras-Kelly","year":"1999","journal-title":"Pharmacotherapy"},{"key":"2025082622473971000_12.4.e226900.10","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1097\/IPC.0b013e318142cbae","article-title":"Ventriculoperitoneal shunt-associated Mycobacterium goodii Infection","volume":"16","author":"Uche","year":"2008","journal-title":"Infectious Diseases in Clinical Practice"},{"key":"2025082622473971000_12.4.e226900.11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-1433.2004.03018.x"},{"key":"2025082622473971000_12.4.e226900.12","doi-asserted-by":"crossref","unstructured":"Tunkel AR , Hasbun R , Bhimraj A , et al . 2017 Infectious Diseases Society of America\u2019s Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis. Clin Infect Dis 2017:1\u201332.doi:10.1093\/cid\/ciw861","DOI":"10.1093\/cid\/ciw861"},{"key":"2025082622473971000_12.4.e226900.13","doi-asserted-by":"crossref","first-page":"2651","DOI":"10.3389\/fmicb.2017.02651","article-title":"Mycobacterium Biofilms","volume":"8","author":"Esteban","year":"2018","journal-title":"Front Microbiol"},{"key":"2025082622473971000_12.4.e226900.14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmyco.2014.11.065"},{"key":"2025082622473971000_12.4.e226900.15","unstructured":"Mayhall CG . Hospital epidemiology and Infection control. 3rd edn. Baltimore,\u00a0Maryland: Lippincott Williams and Wilkins, 2004."}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-226900","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T05:47:50Z","timestamp":1756273670000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-226900"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":15,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2019,4,15]]},"published-print":{"date-parts":[[2019,4]]}},"alternative-id":["10.1136\/bcr-2018-226900"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-226900","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2019,4]]}}}