{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T23:33:53Z","timestamp":1788305633511,"version":"build-2803163510"},"reference-count":17,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bmj.com\/company\/legal-information\/terms-conditions\/legal-information\/tdm-licencepolicy"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2018,10,16]]},"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:p>A 2-month-old girl with normal development and no previous physical illnesses was resuscitated having been found lifeless on her back at home. On admission to Paediatric Intensive Care, she had severe metabolic disturbance, associated with an extremely troubling neurological signs. She died 2\u2009hours later. A full body CT scan did not reveal injury and her parents declined an autopsy. Peripheral blood and cerebrospinal fluid samples were sterile. However, a broad-range PCR coupled with electrospray-ionisation mass spectrometry onto the PLEX-ID automat of peripheral blood revealed the presence of varicella zoster virus. There was a specific viral load in whole blood of 20\u2009542 copies\/ml. It is presumed that Varicella myocarditis was the likely cause of death. Our case illustrates the potential usefulness of a broad range PCR strategy in determining infectious causes of death in sudden infant death. Varicella is a potential cause of sudden infant death.<\/jats:p>","DOI":"10.1136\/bcr-2018-227034","type":"journal-article","created":{"date-parts":[[2018,12,18]],"date-time":"2018-12-18T17:19:47Z","timestamp":1545153587000},"page":"e227034","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Varicella zoster in sudden infant death"],"prefix":"10.1136","volume":"11","author":[{"given":"St\u00e9phane","family":"Dauger","sequence":"first","affiliation":[{"name":"PICU (SMUR) R\u00e9animation P\u00e9diatrique, Assistance Publique \u2013 H\u00f4pitaux de Paris, H\u00f4pital Robert Debr\u00e9, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerome","family":"Le Goff","sequence":"additional","affiliation":[{"name":"Service de Virologie, Assistance Publique, Hopitaux de Paris, Virologie, H\u00f4pital St. Louis, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Deho","sequence":"additional","affiliation":[{"name":"PICU (SMUR) R\u00e9animation P\u00e9diatrique, Assistance Publique \u2013 H\u00f4pitaux de Paris, H\u00f4pital Robert Debr\u00e9, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Jones","sequence":"additional","affiliation":[{"name":"PICU (SMUR) R\u00e9animation P\u00e9diatrique, Assistance Publique \u2013 H\u00f4pitaux de Paris, H\u00f4pital Robert Debr\u00e9, Paris, France"},{"name":"Department of Respiratory, Critical Care and Anesthesia, Institute of Child Heath \u2013 Great Ormond Street, London, UK"},{"name":"UMR 1153, INSERM, Paris, France"},{"name":"SAMU de Paris, Assistance Publique - H\u00f4pitaux de Paris, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2018,11,28]]},"reference":[{"key":"2025082710433569000_11.1.e227034.1","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.12818"},{"key":"2025082710433569000_11.1.e227034.2","doi-asserted-by":"crossref","unstructured":"Garstang JJ , Sidebotham P . 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