{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T18:09:12Z","timestamp":1771006152024,"version":"3.50.1"},"reference-count":22,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,5,15]]},"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:p>A 28-year-old premenopausal woman presented with a painful rapidly growing mass in her right breast and was evaluated with a core needle biopsy, which was suggestive of poorly differentiated carcinoma. Immunohistochemical evaluation revealed primary angiosarcoma of breast. Whole body <jats:sup>18<\/jats:sup>flouro-deoxyglucose positron emission tomography CT showed few metabolically active soft tissue lesions in upper inner quadrant of right breast. The patient underwent breast conservation surgery and in view of positive surgical margins, received adjuvant radiation therapy. Post-treatment completion, the patient has been disease free for 6\u2009months. Primary angiosarcoma of the breast is a rare malignancy which is best managed with a surgery as first approach, with due importance being given to the patient\u2019s perspective on their disease and choices for adjuvant treatment. Decisions in addition to adjuvant radiotherapy need to be made in the multidisciplinary clinic, due to paucity of data.<\/jats:p>","DOI":"10.1136\/bcr-2018-227036","type":"journal-article","created":{"date-parts":[[2019,7,19]],"date-time":"2019-07-19T06:25:13Z","timestamp":1563517513000},"page":"e227036","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["Primary angiosarcoma of the breast: a radiation oncologist\u2019s perspective with a concise review of the literature"],"prefix":"10.1136","volume":"12","author":[{"given":"Rajpal","family":"Singh","sequence":"first","affiliation":[{"name":"Radiation Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kundan Singh","family":"Chufal","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anjali K","family":"Pahuja","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamilarasu","family":"Suresh","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahul Lal","family":"Chowdhary","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2944-6797","authenticated-orcid":false,"given":"Irfan","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,7,18]]},"reference":[{"key":"2025082623465538000_12.7.e227036.1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.216.1.r00jl02197"},{"key":"2025082623465538000_12.7.e227036.2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20010701)92:1<172::AID-CNCR1306>3.0.CO;2-K"},{"key":"2025082623465538000_12.7.e227036.3","first-page":"1","article-title":"Primary breast angiosarcoma: avoiding a common trap","volume":"2011","author":"Desbiens","year":"2011","journal-title":"Case Rep Oncol Med"},{"key":"2025082623465538000_12.7.e227036.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2008.02.053"},{"key":"2025082623465538000_12.7.e227036.5","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-011-1874-1"},{"key":"2025082623465538000_12.7.e227036.6","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/1746-1596-8-14","article-title":"Is mammary not otherwise specified-type sarcoma with CD10 expression a distinct entity? A rare case report with immunohistochemical and ultrastructural study","volume":"8","author":"Yang","year":"2013","journal-title":"Diagn Pathol"},{"key":"2025082623465538000_12.7.e227036.7","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19800715)46:2<368::AID-CNCR2820460226>3.0.CO;2-E"},{"key":"2025082623465538000_12.7.e227036.8","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22784"},{"key":"2025082623465538000_12.7.e227036.9","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/27.2.91"},{"key":"2025082623465538000_12.7.e227036.10","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19881115)62:10<2145::AID-CNCR2820621014>3.0.CO;2-O"},{"key":"2025082623465538000_12.7.e227036.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2007.10.015"},{"key":"2025082623465538000_12.7.e227036.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2006.05.040"},{"key":"2025082623465538000_12.7.e227036.13","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(03)00269-1"},{"key":"2025082623465538000_12.7.e227036.14","first-page":"375","article-title":"Sarcomas of the breast: a multicenter series of 70 cases","volume":"39","author":"Ciatto","year":"1992","journal-title":"Neoplasma"},{"key":"2025082623465538000_12.7.e227036.15","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.06.080"},{"key":"2025082623465538000_12.7.e227036.16","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-8140(99)00070-5"},{"key":"2025082623465538000_12.7.e227036.17","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(99)00444-7"},{"key":"2025082623465538000_12.7.e227036.18","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1995.357"},{"key":"2025082623465538000_12.7.e227036.19","first-page":"105","article-title":"Adjuvant therapy for adult patients with soft tissue sarcomas","volume":"5","author":"Delaney","year":"1991","journal-title":"Oncology"},{"key":"2025082623465538000_12.7.e227036.20","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1200\/JOP.18.00160","article-title":"Fertility preservation in patients with cancer: ASCO clinical practice guideline update summary","volume":"14","author":"Oktay","year":"2018","journal-title":"J Oncol Pract"},{"key":"2025082623465538000_12.7.e227036.21","doi-asserted-by":"crossref","unstructured":"International Commission on Radiation Units and Measurements Report 83. Prescribing, recording, and reporting photon-beam intensity-modulated radiation therapy (IMRT). J Icru 2010;10.","DOI":"10.1093\/jicru\/ndq002"},{"key":"2025082623465538000_12.7.e227036.22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2009.07.1754"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-227036","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T06:47:07Z","timestamp":1756277227000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-227036"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":22,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2019,7,18]]},"published-print":{"date-parts":[[2019,7]]}},"alternative-id":["10.1136\/bcr-2018-227036"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-227036","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7]]}}}