{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T09:55:55Z","timestamp":1756461355612,"version":"3.44.0"},"reference-count":16,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,1,23]]},"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:p>Relapsing polychondritis (RP) is a rare progressive and destructive multisystem disorder characterised by recurrent inflammation of cartilaginous structures. It is a rare disease in paediatrics compared with adults. In children, the diagnosis is either delayed or overlooked due to low incidence. Auricular chondritis has been described in more than half of paediatric cases with RP. However, isolated auricular chondritis has not been reported as the only presentation of pediatric-onset RP. We described a lad who presented with isolated auricular chondritis, which is refractory to conventional treatment, including glucocorticoids and methotrexate as steroid-sparing agent. Remission of his disease\u2019s relapses was sustained with infliximab. Limited auricular involvement as a presenting feature of RP in the absence of systemic association is very rare in children. We describe a case of successful use of infliximab on limited auricular chondritis disease.<\/jats:p>","DOI":"10.1136\/bcr-2018-227043","type":"journal-article","created":{"date-parts":[[2019,5,24]],"date-time":"2019-05-24T06:05:14Z","timestamp":1558677914000},"page":"e227043","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Limited auricular relapsing polychondritis in a child treated successfully with infliximab"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6467-6972","authenticated-orcid":false,"given":"Jubran Theeb","family":"Alqanatish","sequence":"first","affiliation":[{"name":"Department of Paediatrics, King Abdulaziz Medical City and King Saud Bin Abdulaziz University for Health Sciences - Ministry of National Guard, Riyadh, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Basma Ali","family":"Alfarhan","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, King Abdulaziz Medical City and King Saud Bin Abdulaziz University for Health Sciences - Ministry of National Guard, Riyadh, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara Mohammed","family":"Qubaiban","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, King Abdulaziz Medical City and King Saud Bin Abdulaziz University for Health Sciences - Ministry of National Guard, Riyadh, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,5,23]]},"reference":[{"key":"2025082623301239000_12.5.e227043.1","first-page":"301","article-title":"Relapsing polychondritis: commentary","volume":"54","author":"Herrera","year":"2002","journal-title":"Reumatismo"},{"key":"2025082623301239000_12.5.e227043.2","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/0197-0070(89)90024-7","article-title":"Relapsing polychondritis in an adolescent","volume":"10","author":"Trepel","year":"1989","journal-title":"J Adolesc Health Care"},{"key":"2025082623301239000_12.5.e227043.3","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.jpeds.2009.09.045","article-title":"Pediatric-onset relapsing polychondritis: case series and systematic review","volume":"156","author":"Belot","year":"2010","journal-title":"J Pediatr"},{"key":"2025082623301239000_12.5.e227043.4","doi-asserted-by":"publisher","DOI":"10.1007\/s002960000055"},{"key":"2025082623301239000_12.5.e227043.5","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-197605000-00001"},{"key":"2025082623301239000_12.5.e227043.6","doi-asserted-by":"crossref","first-page":"929???946","DOI":"10.1288\/00005537-197906000-00009","article-title":"Relapsing polychondritis-report of ten cases","volume":"89","author":"Damiani","year":"1979","journal-title":"Laryngoscope"},{"key":"2025082623301239000_12.5.e227043.7","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-104-1-74"},{"key":"2025082623301239000_12.5.e227043.8","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(80)80101-8"},{"key":"2025082623301239000_12.5.e227043.9","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.jaut.2014.01.026","article-title":"Diagnosis and classification of relapsing polychondritis","volume":"48-49","author":"Cantarini","year":"2014","journal-title":"J Autoimmun"},{"key":"2025082623301239000_12.5.e227043.10","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.berh.2016.08.001","article-title":"Relapsing polychondritis: A 2016 update on clinical features, diagnostic tools, treatment and biological drug use","volume":"30","author":"Mathian","year":"2016","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"2025082623301239000_12.5.e227043.11","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1097\/01.prs.0000278184.60488.8e","article-title":"Durability of nasal reconstruction in an adolescent with relapsing polychondritis treated with infliximab","volume":"120","author":"Bell","year":"2007","journal-title":"Plast Reconstr Surg"},{"key":"2025082623301239000_12.5.e227043.12","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-009-0981-9"},{"key":"2025082623301239000_12.5.e227043.13","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.080672"},{"key":"2025082623301239000_12.5.e227043.14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.05.010"},{"key":"2025082623301239000_12.5.e227043.15","first-page":"136","article-title":"Complete remission in refractory relapsing polychondritis with intravenous immunoglobulins","volume":"26","author":"Terrier","year":"2008","journal-title":"Clin Exp Rheumatol"},{"key":"2025082623301239000_12.5.e227043.16","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-129-2-199807150-00011"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-227043","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T06:30:23Z","timestamp":1756276223000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-227043"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5]]},"references-count":16,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2019,5,23]]},"published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1136\/bcr-2018-227043"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-227043","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2019,5]]}}}