{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T16:10:01Z","timestamp":1756311001571,"version":"3.44.0"},"reference-count":11,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2018,12,12]]},"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:p>A 46-year-old woman was admitted with tonic-clonic seizures. She was noticed to be withdrawn and low in mood for few months. She had reduced level of consciousness with hyper-reflexia and myoclonus. Metabolic, vasculitic, autoimmune, paraneoplastic and septic screen were normal. Lumbar puncture showed raised protein in the cerebrospinal fluid but the cytology, bacterial and viral screens were negative. A CT of the head revealed global brain swelling consistent with encephalitis which was empirically treated with antibiotics and antiviral therapy. Despite this she continued to have altered sensorium. She had moderately raised titres of antithyroid peroxidise antibodies suggestive of an underlying diagnosis of Hashimoto\u2019s encephalitis. She displayed a significant improvement in her cognitive functions with high-dose steroids which was further in keeping with this rare diagnosis.<\/jats:p>","DOI":"10.1136\/bcr-2018-227190","type":"journal-article","created":{"date-parts":[[2019,1,14]],"date-time":"2019-01-14T12:55:31Z","timestamp":1547470531000},"page":"e227190","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Rare case of Hashimoto\u2019s encephalitis mimicking grief reaction"],"prefix":"10.1136","volume":"12","author":[{"given":"Angeliki","family":"Giannopoulou","sequence":"first","affiliation":[{"name":"Department of Diabetes and Endocrinology, Royal Glamorgan Hospital, Llantrisant, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sajjad","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Department of Diabetes and Endocrinology, Cardiff University, Cardiff, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chandranath","family":"Sarkar","sequence":"additional","affiliation":[{"name":"General Internal Medicine, Royal Glamorgan Hospital, Llantrisant, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atul","family":"Kalhan","sequence":"additional","affiliation":[{"name":"Department of Diabetes and Endocrinology, Royal Glamorgan Hospital, Llantrisant, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,1,14]]},"reference":[{"key":"2025082708460049000_12.1.e227190.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2003.09.007"},{"key":"2025082708460049000_12.1.e227190.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(66)92876-5"},{"key":"2025082708460049000_12.1.e227190.3","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.60.2.164"},{"key":"2025082708460049000_12.1.e227190.4","doi-asserted-by":"crossref","first-page":"506","DOI":"10.5812\/ijem.4174","article-title":"Hashimoto encephalopathy: a rare intricate syndrome","volume":"10","author":"Payer","year":"2012","journal-title":"Int J Endocrinol Metab"},{"key":"2025082708460049000_12.1.e227190.5","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/j.seizure.2011.04.011","article-title":"Infectious disease or Hashimoto\u2019s encephalopathy flares: a case report","volume":"20","author":"Huang","year":"2011","journal-title":"Seizure"},{"key":"2025082708460049000_12.1.e227190.6","first-page":"169","article-title":"Acute psychiatric presentation of steroid-responsive encephalopathy: the under recognized side of autoimmune thyroiditis","volume":"48","author":"Carlone","year":"2013","journal-title":"Riv Psichiatr"},{"key":"2025082708460049000_12.1.e227190.7","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.54.3.769"},{"key":"2025082708460049000_12.1.e227190.8","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/j.jfma.2011.05.012","article-title":"Hashimoto\u2019s encephalopathy: report of three cases","volume":"113","author":"Chang","year":"2014","journal-title":"J Formos Med Assoc"},{"key":"2025082708460049000_12.1.e227190.9","first-page":"893","article-title":"[The biomarker and treatment in Hashimoto\u2019s encephalopahty]","volume":"71","author":"Kishitani","year":"2013","journal-title":"Nihon Rinsho"},{"key":"2025082708460049000_12.1.e227190.10","first-page":"1541","article-title":"Reversible MR angiographic findings in a patient with autoimmune Graves disease","volume":"25","author":"Utku","year":"2004","journal-title":"AJNR Am J Neuroradiol"},{"key":"2025082708460049000_12.1.e227190.11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2010.01967.x"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-227190","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T15:46:08Z","timestamp":1756309568000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-227190"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2019,1,14]]},"published-print":{"date-parts":[[2019,1]]}},"alternative-id":["10.1136\/bcr-2018-227190"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-227190","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2019,1]]}}}