{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T05:49:20Z","timestamp":1762926560702,"version":"3.44.0"},"reference-count":11,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bmj.com\/company\/legal-information\/terms-conditions\/legal-information\/tdm-licencepolicy"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2018,10,26]]},"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:p>Cryptococcosis is an invasive fungal infection caused by encapsulated yeasts of the <jats:italic>Cryptococcus<\/jats:italic> species. Inoculation usually occurs by inhalation through the respiratory tract, where it can then spread haematogenously to various sites, such as the central nervous system or the skin, in susceptible patients. We present the case of a 68-year-old male patient on long-term steroids who presented with a right upper limb cellulitis not responding to antibiotics. This was subsequently diagnosed as cryptococcal cellulitis on an urgent skin biopsy. Wound swabs and blood cultures, which were initially negative, were repeated and confirmed the presence of disseminated cryptococcal disease. The patient\u2019s neighbours kept racing pigeons and this was hypothesised as a potential source of infection.<\/jats:p>","DOI":"10.1136\/bcr-2018-227249","type":"journal-article","created":{"date-parts":[[2018,12,12]],"date-time":"2018-12-12T07:11:12Z","timestamp":1544598672000},"page":"e227249","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Disseminated cryptococcal infection initially presenting as cryptococcal cellulitis in an HIV-negative patient on long-term steroids"],"prefix":"10.1136","volume":"11","author":[{"given":"Colm","family":"Kerr","sequence":"first","affiliation":[{"name":"Infectious Diseases, Cork University Hospital Group, Cork, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William A","family":"Stack","sequence":"additional","affiliation":[{"name":"Gastroenterology and General Medicine, Bon Secours Hospital, Cork, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corinna","family":"Sadlier","sequence":"additional","affiliation":[{"name":"Acute Medicine\/Infectious Diseases, Cork University Hospital Group, Cork, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arthur","family":"Jackson","sequence":"additional","affiliation":[{"name":"Infectious Diseases, Cork University Hospital\/Mercy University Hospital, Cork, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,11,28]]},"reference":[{"key":"2025082711323295000_11.1.e227249.1","doi-asserted-by":"crossref","DOI":"10.1542\/peds.107.5.e66","article-title":"Serologic evidence for Cryptococcus neoformans infection in early childhood","volume":"107","author":"Goldman","year":"2001","journal-title":"Pediatrics"},{"key":"2025082711323295000_11.1.e227249.2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(17)30243-8"},{"key":"2025082711323295000_11.1.e227249.3","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0043582","article-title":"Comparison and temporal trends of three groups with cryptococcosis: HIV-infected, solid organ transplant, and HIV-negative\/non-transplant","volume":"7","author":"Bratton","year":"2012","journal-title":"PLoS One"},{"key":"2025082711323295000_11.1.e227249.4","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1977.03270340058022"},{"key":"2025082711323295000_11.1.e227249.5","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/14.3.666"},{"key":"2025082711323295000_11.1.e227249.6","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1007\/s40588-017-0064-8","article-title":"Cryptococcosis today: It is not all about HIV infection","volume":"4","author":"O\u2019Halloran","year":"2017","journal-title":"Curr Clin Microbiol Rep"},{"key":"2025082711323295000_11.1.e227249.7","doi-asserted-by":"crossref","unstructured":"Poenaru SM , Rofaiel R , Hosseini-Moghaddam SM . Cryptococcus neoformans osteomyelitis and intramuscular abscess in a liver transplant patient. BMJ Case Rep 2017. doi: 10.1136\/bcr-2017-221650. 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