{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T16:36:32Z","timestamp":1790613392694,"version":"4.1.0"},"reference-count":16,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.bmj.com\/company\/legal-information\/terms-conditions\/legal-information\/tdm-licencepolicy"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2018,10,23]]},"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:p>A middle-aged man presented to emergency services with central vision loss in the setting of flu-like illness with fever. A striking subfoveal abscess was observed in the right fundus. Focal acute chorioretinal inflammation was noted in the asymptomatic fellow eye. <jats:italic>Staphylococcus aureus<\/jats:italic> septicaemia was subsequently diagnosed. He presented with undiagnosed HIV infection and latent syphilis. Serial high-definition multimodal retinal imaging showcased resolution of the dome-shaped subretinal abscess following treatment with intravenous flucloxacillin. A chorioretinal scar swiftly replaced the subfoveal abscess. Peripheral right vision and full left vision was retained. Vision loss due to endogenous endophthalmitis in systemic sepsis is an emergency requiring prompt multidisciplinary care. Sight and life are at risk\u2014thus this is not a diagnosis to miss! Early recognition is paramount to health and in retaining vision. We briefly review relevant literature and portray how multimodal imaging guided response to treatment of acute subretinal abscess.<\/jats:p>","DOI":"10.1136\/bcr-2018-227288","type":"journal-article","created":{"date-parts":[[2018,12,18]],"date-time":"2018-12-18T17:19:47Z","timestamp":1545153587000},"page":"e227288","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Acute subretinal abscess in <i>Staphylococcus aureus<\/i> septicaemia with endophthalmitis showcased by multimodal retinal imaging and with 2-year follow-up"],"prefix":"10.1136","volume":"11","author":[{"given":"Rita","family":"Prajapati","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Royal Bolton Hospital NHS Foundation Trust, Bolton, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pippa","family":"Newton","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Manchester University NHS Foundation Trust, Manchester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sameena","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Department of Sexual Medicine, Manchester University NHS Foundation Trust, Manchester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Kelly","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Royal Bolton Hospital NHS Foundation Trust, Bolton, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2018,11,28]]},"reference":[{"key":"2025082622410114000_11.1.e227288.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2014.06.002"},{"key":"2025082622410114000_11.1.e227288.2","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1038\/eye.2017.284","article-title":"A British Ophthalmological Surveillance Unit Study on metastatic endogenous endophthalmitis","volume":"32","author":"Maling","year":"2018","journal-title":"Eye"},{"key":"2025082622410114000_11.1.e227288.3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2015\/261310","article-title":"An eleven-year retrospective study of endogenous bacterial endophthalmitis","volume":"2015","author":"Nishida","year":"2015","journal-title":"J Ophthalmol"},{"key":"2025082622410114000_11.1.e227288.4","doi-asserted-by":"crossref","first-page":"134","DOI":"10.3928\/23258160-20170130-07","article-title":"Clinical features and management of subretinal abscesses secondary to methicillin-resistant staphylococcus aureus endogenous endophthalmitis","volume":"48","author":"Fortun","year":"2017","journal-title":"Ophthalmic Surg Lasers Imaging Retina"},{"key":"2025082622410114000_11.1.e227288.5","doi-asserted-by":"publisher","DOI":"10.1186\/s12348-015-0063-y"},{"key":"2025082622410114000_11.1.e227288.6","doi-asserted-by":"crossref","first-page":"894","DOI":"10.3928\/23258160-20171030-04","article-title":"Optical coherence tomography findings in endogenous fungal chorioretinitis, retinitis, and endophthalmitis","volume":"48","author":"Stephens","year":"2017","journal-title":"Ophthalmic Surg Lasers Imaging Retina"},{"key":"2025082622410114000_11.1.e227288.7","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/S1473-3099(13)70216-0","article-title":"A high-definition view of endogenous fungal endophthalmitis","volume":"14","author":"Rodrigues","year":"2014","journal-title":"Lancet Infect Dis"},{"key":"2025082622410114000_11.1.e227288.8","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.1097\/IAE.0000000000000135","article-title":"Multimodal imaging findings in endogenous Aspergillus endophthalmitis","volume":"34","author":"Adam","year":"2014","journal-title":"Retina"},{"key":"2025082622410114000_11.1.e227288.9","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s12348-015-0054-z","article-title":"Multimodal imaging of refractory Candida chorioretinitis progressing to endogenous endophthalmitis","volume":"5","author":"Lavine","year":"2015","journal-title":"J Ophthalmic Inflamm Infect"},{"key":"2025082622410114000_11.1.e227288.10","first-page":"518","article-title":"Endogenous cryptococcal endophthalmitis in immunocompetent host: case report and review of multimodal imaging findings and treatment","volume":"26","author":"Amphornphruet","year":"2018","journal-title":"Ocul Immunol Inflamm"},{"key":"2025082622410114000_11.1.e227288.11","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1097\/IAE.0000000000001630","article-title":"Spectral domain optical coherence tomography findings in endogenous candida endophthalmitis and their clinical relevance","volume":"38","author":"Invernizzi","year":"2018","journal-title":"Retina"},{"key":"2025082622410114000_11.1.e227288.12","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00134-14"},{"key":"2025082622410114000_11.1.e227288.13","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02651-15"},{"key":"2025082622410114000_11.1.e227288.14","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1038\/eye.2015.200","article-title":"Staphylococcal endogenous endophthalmitis in association with pyogenic vertebral osteomyelitis","volume":"30","author":"Steeples","year":"2016","journal-title":"Eye"},{"key":"2025082622410114000_11.1.e227288.15","doi-asserted-by":"crossref","first-page":"e97","DOI":"10.1016\/j.jcjo.2016.11.016","article-title":"Endogenous methicillin-resistant Staphylococcus aureus endophthalmitis secondary to axillary phlegmon: a case report","volume":"52","author":"Kansal","year":"2017","journal-title":"Can J Ophthalmol"},{"key":"2025082622410114000_11.1.e227288.16","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.sjopt.2015.11.003","article-title":"Endogenous bacterial endophthalmitis masquerading as an intraocular tumor","volume":"30","author":"Salvetti","year":"2016","journal-title":"Saudi J Ophthalmol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/data.bmj.org\/tdm\/10.1136\/bcr-2018-227288","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-227288","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T05:41:11Z","timestamp":1756273271000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-227288"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":16,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2018,11,28]]},"published-print":{"date-parts":[[2018,11]]}},"alternative-id":["10.1136\/bcr-2018-227288"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-227288","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11]]}}}