{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T19:38:00Z","timestamp":1783798680031,"version":"3.55.0"},"reference-count":14,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,1,10]]},"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:p>We report a case of septic thrombosis of the right cavernous sinus in a diabetic woman in her late 70\u2019s due to ipsilateral sphenoid sinusitis. The diagnosis was delayed and made only after the abrupt and dramatic appearance of the manifestations of sinus thrombosis. The patient developed, among the other symptoms, right peripheral facial palsy, which is a very rare manifestation in cavernous sinus thrombosis (CST). She was treated with broad-spectrum antibiotics and enoxaparin. The day of the scheduled drainage of sphenoid sinus\u201424\u2009hours after the initiation of anticoagulation\u2014she developed fatal subarachnoid haemorrhage. Our case demonstrates the difficulty of timely diagnosis of acute sphenoid sinusitis which has emerged as the most common primary infectious source potentially leading in CST. It also underscores the uncertainty concerning the use of anticoagulation in cerebral sinus thrombosis of infectious origin.<\/jats:p>","DOI":"10.1136\/bcr-2018-227302","type":"journal-article","created":{"date-parts":[[2019,1,30]],"date-time":"2019-01-30T23:08:58Z","timestamp":1548889738000},"page":"e227302","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":20,"title":["Cavernous sinus thrombosis due to ipsilateral sphenoid sinusitis"],"prefix":"10.1136","volume":"12","author":[{"given":"Christodoulos","family":"Dolapsakis","sequence":"first","affiliation":[{"name":"3rd Department of Medicine, Evaggelismos General Hospital, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleftheria","family":"Kranidioti","sequence":"additional","affiliation":[{"name":"3rd Department of Medicine, Evaggelismos General Hospital, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"Katsila","sequence":"additional","affiliation":[{"name":"3rd Department of Medicine, Evaggelismos General Hospital, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9630-9712","authenticated-orcid":false,"given":"Michael","family":"Samarkos","sequence":"additional","affiliation":[{"name":"1st Department of Medicine, Laikon Hospital, Athens, Greece"},{"name":"National and Kapodistrian University of Athens - Faculty of Medicine, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2019,1,29]]},"reference":[{"key":"2025082623150026000_12.1.e227302.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra042354"},{"key":"2025082623150026000_12.1.e227302.2","doi-asserted-by":"crossref","first-page":"9:9","DOI":"10.1186\/1746-160X-9-9","article-title":"Cavernous sinus thrombosis caused by contralateral sphenoid sinusitis: a case report","volume":"9","author":"Komatsu","year":"2013","journal-title":"Head Face Med"},{"key":"2025082623150026000_12.1.e227302.3","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0385-8146(01)00108-0","article-title":"The intracranial complication of acute isolated sphenoid sinusitis","volume":"29","author":"Unlu","year":"2002","journal-title":"Auris Nasus Larynx"},{"key":"2025082623150026000_12.1.e227302.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2011.09.048"},{"key":"2025082623150026000_12.1.e227302.5","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s12070-007-0048-8","article-title":"An atypical presentation of cavernous sinus thrombosis","volume":"59","author":"Ramanand","year":"2007","journal-title":"Indian J Otolaryngol Head Neck Surg"},{"key":"2025082623150026000_12.1.e227302.6","doi-asserted-by":"crossref","first-page":"1766","DOI":"10.1161\/01.STR.31.7.1766","article-title":"Facial palsy in cerebral venous thrombosis : transcranial stimulation and pathophysiological considerations","volume":"31","author":"Straub","year":"2000","journal-title":"Stroke"},{"key":"2025082623150026000_12.1.e227302.7","first-page":"79","article-title":"A rare localization of cerebral venous sinus thrombosis. 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