{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T11:42:43Z","timestamp":1756381363269,"version":"3.44.0"},"reference-count":13,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,1,7]]},"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:p>We report the case of a 32-year-old Afrocaribbean man with known stage 3 proliferative sickle-cell retinopathy who presented with a mixed picture of tractional and rhegmatogenous macula off detachment. He underwent left primary 25\u2009g vitrectomy with silicone oil, delamination and endolaser photocoagulation under a general anaesthetic. He, however, presented 48\u2009hours postoperatively with gross anterior segment ischaemia. His pain and ocular signs settled over the course of a few days following administration of supplemental oxygen, oral steroids, analgesia and intravenous hydration. Examination showed resolution of his proptosis and orbital signs as well as anterior segment inflammation. He remains under follow-up.<\/jats:p>","DOI":"10.1136\/bcr-2018-227541","type":"journal-article","created":{"date-parts":[[2019,1,30]],"date-time":"2019-01-30T23:09:05Z","timestamp":1548889745000},"page":"e227541","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Gross anterior segment ischaemia following vitreoretinal surgery for sickle-cell retinopathy"],"prefix":"10.1136","volume":"12","author":[{"given":"Andrew","family":"Walkden","sequence":"first","affiliation":[{"name":"Vitreo-retinal Unit, Manchester Royal Eye Hospital, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6067-8417","authenticated-orcid":false,"given":"Benjamin","family":"Griffin","sequence":"additional","affiliation":[{"name":"Manchester University NHS Foundation Trust, Manchester Royal Eye Hospital, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clarissa","family":"Cheng","sequence":"additional","affiliation":[{"name":"Ophthalmology, Tan Tock Seng Hospital, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe","family":"Dhawahir-Scala","sequence":"additional","affiliation":[{"name":"Vitreo-retinal Unit, Manchester Royal Eye Hospital, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,1,29]]},"reference":[{"key":"2025082804060234000_12.1.e227541.1","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1097\/00006982-200204000-00014","article-title":"Anterior segment ischemia after vitrectomy in sickle cell disease","volume":"22","author":"Leen","year":"2002","journal-title":"Retina"},{"key":"2025082804060234000_12.1.e227541.2","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1056\/NEJMra1510865","article-title":"Sickle cell disease","volume":"376","author":"Piel","year":"2017","journal-title":"N Engl J Med Overseas Ed"},{"key":"2025082804060234000_12.1.e227541.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2009.11.004"},{"key":"2025082804060234000_12.1.e227541.4","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0002-9394(71)91588-1","article-title":"Anterior segment ischemia following scleral buckling in sickle cell hemoglobinopathy","volume":"72","author":"Ryan","year":"1971","journal-title":"Am J Ophthalmol"},{"key":"2025082804060234000_12.1.e227541.5","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1038\/s41433-018-0127-y","article-title":"A comparison of 23-gauge and 20-gauge vitrectomy for proliferative sickle cell retinopathy - clinical outcomes and surgical management","volume":"32","author":"Ho","year":"2018","journal-title":"Eye"},{"key":"2025082804060234000_12.1.e227541.6","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1038\/eye.2008.296","article-title":"Vitreoretinal management of the complications of sickle cell retinopathy by observation or pars plana vitrectomy","volume":"23","author":"Williamson","year":"2009","journal-title":"Eye"},{"key":"2025082804060234000_12.1.e227541.7","doi-asserted-by":"crossref","unstructured":"Myint KT , Sahoo S , Thein AW , et al . 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