{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T19:15:26Z","timestamp":1757704526616,"version":"3.44.0"},"reference-count":15,"publisher":"BMJ","issue":"9","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,8,27]]},"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:p>Women with a multiple pregnancy are at increased risk of developing hypertensive disorders of pregnancy. We describe a case of a dichorionic triamniotic triplet pregnancy complicated by severe hypertension, proteinuria and maternal symptoms, fitting with the diagnosis of pre-eclampsia, apart from the early gestational age of only 16 weeks. After reduction of the monochorionic pair, the disease resolved and pre-eclampsia was diagnosed again at 30 weeks of gestation, resulting in a delivery on maternal indication at 33 weeks of gestation. In a review of the literature, we found six papers including eight cases on multifetal pregnancy reduction on maternal indication. Multifetal pregnancy reduction resulted in a prolongation of pregnancy of two to 21 weeks and may be considered in extreme early onset pre-eclampsia in dichorionic multiple pregnancies.<\/jats:p>","DOI":"10.1136\/bcr-2018-227667","type":"journal-article","created":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T07:25:14Z","timestamp":1568877914000},"page":"e227667","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Recovery of second trimester pre-eclampsia after fetal reduction of a triplet"],"prefix":"10.1136","volume":"12","author":[{"given":"Jeske M","family":"bij de Weg","sequence":"first","affiliation":[{"name":"Obstetrics and Gynaecology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christianne J","family":"de Groot","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Pajkrt","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marjon A","family":"de Boer","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,9,18]]},"reference":[{"key":"2025082801205722000_12.9.e227667.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.08.009"},{"key":"2025082801205722000_12.9.e227667.2","doi-asserted-by":"crossref","first-page":"536.e1","DOI":"10.1016\/j.ajog.2014.04.023","article-title":"The effectiveness of multifetal pregnancy reduction in trichorionic triplet gestation","volume":"211","author":"van de Mheen","year":"2014","journal-title":"Am J Obstet Gynecol"},{"key":"2025082801205722000_12.9.e227667.3","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1159\/000441650","article-title":"Outcome of multifetal pregnancy reduction in women with a dichorionic triamniotic triplet pregnancy to a singleton pregnancy: A retrospective nationwide cohort study","volume":"40","author":"van de Mheen","year":"2016","journal-title":"Fetal Diagn Ther"},{"key":"2025082801205722000_12.9.e227667.4","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/s00404-014-3175-y","article-title":"A comparative study of obstetric outcomes in electively or spontaneously reduced triplet pregnancies","volume":"290","author":"Okyay","year":"2014","journal-title":"Arch Gynecol Obstet"},{"key":"2025082801205722000_12.9.e227667.5","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0028-2243(94)90271-2","article-title":"Single fetal demise in twin gestation resulting in the resolution of severe pre-eclampsia","volume":"56","author":"Hagay","year":"1994","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"2025082801205722000_12.9.e227667.6","first-page":"1369-72","article-title":"[Foeto-foetal conflict of interests in multiple pregnancies with severe discordant growth; 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