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Cholecystectomy is the only effective treatment option for cholesterolosis and can be performed safely during pregnancy. Cholecystectomy in pregnancy should be considered if, despite atypical symptoms, gallbladder disease is suspected and other diagnoses are ruled out. This may reduce recurrent symptoms, hospital admissions, exposure to harmful drugs and obstetric complications.<\/jats:p>","DOI":"10.1136\/bcr-2018-227826","type":"journal-article","created":{"date-parts":[[2019,3,21]],"date-time":"2019-03-21T05:17:41Z","timestamp":1553145461000},"page":"e227826","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Abdominal pain and vomiting during pregnancy due to cholesterolosis"],"prefix":"10.1136","volume":"12","author":[{"given":"Emilie VJ","family":"van Limburg Stirum","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, OLVG, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria G","family":"van Pampus","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, OLVG, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeroen M","family":"Jansen","sequence":"additional","affiliation":[{"name":"Department of Gastro-enterology, OLVG, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erica WM","family":"Janszen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, OLVG, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,3,20]]},"reference":[{"key":"2025082700132717000_12.3.e227826.1","doi-asserted-by":"crossref","first-page":"2492","DOI":"10.1080\/14767058.2017.1342805","article-title":"Interventions for treating hyperemesis gravidarum: a Cochrane systematic review and meta-analysis","volume":"31","author":"Boelig","year":"2018","journal-title":"J Matern Fetal Neonatal Med"},{"key":"2025082700132717000_12.3.e227826.2","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-009-0544-x"},{"key":"2025082700132717000_12.3.e227826.3","first-page":"53","article-title":"Surgery for gallstone disease during pregnancy does not increase fetal or maternal mortality: a meta-analysis","volume":"5","author":"Athwal","year":"2016","journal-title":"Hepatobiliary Surg Nutr"},{"key":"2025082700132717000_12.3.e227826.4","unstructured":"Pearl JP , Price RR , Tonkin AE , et al . 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