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Cross-sectional imaging ruled out metastases and the patient underwent radical urethrectomy, vaginal reconstruction and Mitrofanoff urinary diversion. The patient declined adjuvant chemotherapy and remained under regular surveillance. MANECs are uncommon tumours and treatment was therefore guided by expert opinion. A multidisciplinary approach is essential with the early involvement of surgeons, oncologists, histopathologist, radiologist and neuroendocrine specialists.<\/jats:p>","DOI":"10.1136\/bcr-2018-227948","type":"journal-article","created":{"date-parts":[[2019,3,22]],"date-time":"2019-03-22T06:45:19Z","timestamp":1553237119000},"page":"e227948","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Mixed adenoneuroendocrine carcinoma of the urethra"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0496-4985","authenticated-orcid":false,"given":"Nicholas","family":"Raison","sequence":"first","affiliation":[{"name":"Department of Urology, Royal Free London NHS Foundation Trust, London, UK"},{"name":"Division of Transplantation Immunology and Mucosal Biology, King\u2019s College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ursula","family":"McGovern","sequence":"additional","affiliation":[{"name":"Department of Oncology, The Royal Free NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Hines","sequence":"additional","affiliation":[{"name":"Department of Urology, University College London Hospitals NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitrios","family":"Volanis","sequence":"additional","affiliation":[{"name":"Department of Urology, Royal Free London NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,3,21]]},"reference":[{"key":"2025082708593238000_12.3.e227948.1","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.ejca.2011.10.031","article-title":"Incidence and survival of rare urogenital cancers in Europe","volume":"48","author":"Visser","year":"2012","journal-title":"Eur J Cancer"},{"key":"2025082708593238000_12.3.e227948.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2006.08.1057"},{"key":"2025082708593238000_12.3.e227948.3","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(91)90003-8"},{"key":"2025082708593238000_12.3.e227948.4","unstructured":"Bosman FT . 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