{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T19:17:13Z","timestamp":1762543033460,"version":"3.44.0"},"reference-count":8,"publisher":"BMJ","issue":"4","funder":[{"DOI":"10.13039\/501100008331","name":"Universidade Federal do Rio de Janeiro","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008331","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,3,25]]},"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:p>Brainstem gliomas are rare tumours in adults, accounting for only 1%\u20132% of all intracranial gliomas. They are recognised as a heterogeneous group, in which most are malignant tumours. Brainstem gliomas are classified into four major groups according to the growth pattern on imaging, namely diffuse, focal, exophytic and cervicomedullary. Such a classification system is also useful for surgical decision making. The exophytic variant is extremely rare having anecdoctal reports in the literature. We report the case of an adult patient affected by an exophytic glioblastoma of the pons, which was submitted to subtotal resection followed by radiation therapy and chemotherapy with a longer overall survival. To the best of our knowledge, this is the seventh adult patient reported of an exophytic brainstem glioblastoma.<\/jats:p>","DOI":"10.1136\/bcr-2018-228105","type":"journal-article","created":{"date-parts":[[2019,4,17]],"date-time":"2019-04-17T07:16:01Z","timestamp":1555485361000},"page":"e228105","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Dorsally exophytic glioblastoma of the pons"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6224-5001","authenticated-orcid":false,"given":"Marco Antonio","family":"Negreiros","sequence":"first","affiliation":[{"name":"Departamento de Especialidades Cir\u00fargicas, Universidade Federal do Rio de Janeiro Hospital Universitario Clementino Fraga Filho, Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fred Franklin","family":"Batista","sequence":"additional","affiliation":[{"name":"Departamento de Especialidades Cir\u00fargicas, Universidade Federal do Rio de Janeiro Hospital Universitario Clementino Fraga Filho, Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaeanny Bianchini","family":"Cottar","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Neurocirurgia, Hospital Federal do Andara\u00ed"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3998-2171","authenticated-orcid":false,"given":"Marcus Andr\u00e9","family":"Acioly","sequence":"additional","affiliation":[{"name":"Departamento de Especialidades Cir\u00fargicas, Universidade Federal do Rio de Janeiro Hospital Universitario Clementino Fraga Filho, Rio de Janeiro, Brazil"},{"name":"Departamento de Especialidades Cir\u00fargicas, Universidade Federal Fluminense Faculdade de Medicina, Niteroi, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,4,16]]},"reference":[{"key":"2025082713070752000_12.4.e228105.1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/124.12.2528"},{"key":"2025082713070752000_12.4.e228105.2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1993.78.3.0408"},{"key":"2025082713070752000_12.4.e228105.3","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.jocn.2003.02.007","article-title":"Gross total surgical removal of malignant glioma from the medulla oblongata: report of two adult cases with reference to surgical anatomy","volume":"11","author":"Kyoshima","year":"2004","journal-title":"J Clin Neurosci"},{"key":"2025082713070752000_12.4.e228105.4","doi-asserted-by":"publisher","DOI":"10.3171\/2008.8.JNS17644"},{"key":"2025082713070752000_12.4.e228105.5","doi-asserted-by":"crossref","first-page":"36","DOI":"10.4103\/1793-5482.95697","article-title":"Primary glioblastoma multiforme of medulla oblongata: Case report and review of literature","volume":"7","author":"Chotai","year":"2012","journal-title":"Asian J Neurosurg"},{"key":"2025082713070752000_12.4.e228105.6","doi-asserted-by":"crossref","first-page":"96","DOI":"10.3109\/02688697.2011.585670","article-title":"An exophytic brain stem glioblastoma in an elderly presenting as a cerebellopontine angle syndrome","volume":"26","author":"Salunke","year":"2012","journal-title":"Br J Neurosurg"},{"key":"2025082713070752000_12.4.e228105.7","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1016\/j.clineuro.2012.02.022","article-title":"Fourth ventricle glioblastoma","volume":"114","author":"Zhang","year":"2012","journal-title":"Clin Neurol Neurosurg"},{"key":"2025082713070752000_12.4.e228105.8","doi-asserted-by":"crossref","first-page":"224","DOI":"10.4103\/1793-5482.144151","article-title":"Dorsally exophytic glioblastoma arising from the medulla oblongata in an adult presenting as 4\n                  th\n                ventricular mass","volume":"12","author":"Das","year":"2017","journal-title":"Asian J Neurosurg"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2018-228105","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T20:07:14Z","timestamp":1756325234000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2018-228105"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":8,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2019,4,16]]},"published-print":{"date-parts":[[2019,4]]}},"alternative-id":["10.1136\/bcr-2018-228105"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2018-228105","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2019,4]]}}}