{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T17:30:34Z","timestamp":1787679034871,"version":"build-2784847793"},"reference-count":9,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,3,22]]},"published-print":{"date-parts":[[2019,4]]},"abstract":"A 51-year-old man with a medical history of coronary artery disease and dyslipidaemia presented with acute myocardial infarction resulting in cardiogenic shock, necessitating intra-aortic balloon pump placement and extracorporeal membrane oxygenation (ECMO). His hospital course was complicated by several infectious complications including ECMO circuit Pseudomonas aeruginosa<\/jats:italic> bloodstream infection and presumed infected right atrial thrombus. He subsequently underwent urgent left ventricular assist device placement and had a prolonged hospital stay. On day 100 of admission, he developed acute hypoxic respiratory distress with new pulmonary infiltrates. Sputum cultures grew Cryptococcus neoformans<\/jats:italic>. Blood culture also grew C. neoformans<\/jats:italic> after 96\u2009hours of incubation and cryptococcal serum antigen was elevated at 1:20. Cerebrospinal fluid studies from a lumbar puncture were normal. He was treated with 2\u2009weeks of combination antifungal therapy followed by life-long fluconazole suppression.<\/jats:p>","DOI":"10.1136\/bcr-2018-228283","type":"journal-article","created":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T07:14:09Z","timestamp":1554794049000},"page":"e228283","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Disseminated Cryptococcus neoformans<\/i> infection in a left ventricular assist device recipient"],"prefix":"10.1136","volume":"12","author":[{"given":"Deeksha","family":"Jandhyala","sequence":"first","affiliation":[{"name":"Internal Medicine, College of Medicine, Medical University of South Carolina, Charleston, South Carolina, USA"},{"name":"Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugene M","family":"Tan","sequence":"additional","affiliation":[{"name":"Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David Cook","family":"Stahr","sequence":"additional","affiliation":[{"name":"Oral and Maxillofacial Surgery, West Virginia University, Morgantown, West Virginia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6499-5543","authenticated-orcid":false,"given":"Muhammad Rizwan","family":"Sohail","sequence":"additional","affiliation":[{"name":"ID, Mayo Clinic, Rochester, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2019,4,8]]},"reference":[{"key":"2025082800575364000_12.4.e228283.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)10359-8"},{"key":"2025082800575364000_12.4.e228283.2","doi-asserted-by":"crossref","unstructured":"Kauffman CA , Pappas PG , Sobel JD , et al . 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