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Ceftaroline was later added, due to the high burden of disease and difficulty in clearing her infection. After initiation of ceftaroline, bacteraemia cleared and mental status improved, however, she developed haemolytic anaemia. Ceftaroline was stopped and vancomycin continued. Staphylococcal meningitis is a rare occurrence, estimated at a rate of only 1%\u201310% of all bacterial meningitis cases. Ceftaroline seems to be a suitable option for disseminated MRSA infection, including MRSA meningitis, when the clinical response to vancomycin is inadequate. Further studies are warranted in order to establish adequate dosing while avoiding adverse effects.<\/jats:p>","DOI":"10.1136\/bcr-2018-229114","type":"journal-article","created":{"date-parts":[[2019,8,29]],"date-time":"2019-08-29T07:34:18Z","timestamp":1567064058000},"page":"e229114","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Methicillin-resistant <i>Staphylococcus aureus<\/i> (MRSA) sepsis complicated by warm autoimmune haemolytic anaemia secondary to antimicrobial therapy"],"prefix":"10.1136","volume":"12","author":[{"given":"Jorge","family":"Verdecia","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, University of Florida Health at Jacksonville, Jacksonville, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jarelys","family":"Hernandez","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Florida Health at Jacksonville, Jacksonville, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Izzo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Florida Health at Jacksonville, Jacksonville, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"Sottile","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Florida Health at Jacksonville, Jacksonville, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Isache","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Florida Health at Jacksonville, Jacksonville, Florida, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,8,28]]},"reference":[{"key":"2025082708420220000_12.8.e229114.1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0b013e318243442b"},{"key":"2025082708420220000_12.8.e229114.2","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1155\/2004\/125983","article-title":"A case of spontaneous methicillin-resistant Staphylococcus aureus meningitis in a health care worker","volume":"15","author":"Dylewski","year":"2004","journal-title":"Can J Infect Dis Med Microbiol"},{"key":"2025082708420220000_12.8.e229114.3","doi-asserted-by":"publisher","DOI":"10.1016\/S1684-1182(10)60073-4"},{"key":"2025082708420220000_12.8.e229114.4","doi-asserted-by":"crossref","first-page":"909.e1","DOI":"10.1016\/j.ajem.2018.01.098","article-title":"Spontaneous methicillin-resistant Staphylococcus aureus (MRSA) meningitis","volume":"36","author":"Longhurst","year":"2018","journal-title":"Am J Emerg Med"},{"key":"2025082708420220000_12.8.e229114.5","unstructured":"Johnson KS , Sexton DJ . 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