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Due to the sight-threatening disease, the patient underwent surgical intervention with intrastromal injection of amphotericin B and a large conjunctival flap covering 75% of the right eye corneal ulcer. After 3\u2009months of therapy, she had near-complete resolution of the corneal ulcer. Unfortunately, recurrence of the corneal ulcer occurred within 3 weeks of cessation of therapy, prompting reinitiation of ophthalmic and systemic antifungal agents. The patient was advised to continue therapy for 6 months with regular follow-up.<\/jats:p>","DOI":"10.1136\/bcr-2019-229226","type":"journal-article","created":{"date-parts":[[2019,4,25]],"date-time":"2019-04-25T06:01:48Z","timestamp":1556172108000},"page":"e229226","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Recalcitrant <i>Paecilomyces<\/i> keratitis"],"prefix":"10.1136","volume":"12","author":[{"given":"Seetha","family":"Lakshmi","sequence":"first","affiliation":[{"name":"Department of Infectious Disease, University of South Florida, Tampa, Florida, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina Vanessa","family":"Garcia","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease, University of South Florida, Tampa, Florida, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2019,4,24]]},"reference":[{"key":"2025082800121154000_12.4.e229226.1","unstructured":"Onofrey BE , Skorin L , Holdeman NR . 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A masquerader? Paecilomyces must be distinguished from Penicillium in fungal keratitis: a report of two contrasting cases. 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