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Despite treatment with high-dose oral glucocorticoid (GC) and multiple pulses of intravenous methylprednisolone, his vision deteriorated to hand movements in one eye. 8\u2009mg\/kg intravenous tocilizumab, a humanised, recombinant anti-IL-6 receptor antibody, was administered within 48\u2009hours of vision loss and continued monthly, resulting in marked visual improvement within days, as well as sustained remission of GCA. This case suggests a possible role for tocilizumab as a rescue therapy to prevent or recover visual loss in patients with GCA resistant to GC treatment, termed refractory GCA. Further research is required to elucidate the role of intravenous administration of tocilizumab in this setting.<\/jats:p>","DOI":"10.1136\/bcr-2019-229236","type":"journal-article","created":{"date-parts":[[2019,10,5]],"date-time":"2019-10-05T14:55:29Z","timestamp":1570287329000},"page":"e229236","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":12,"title":["Rapid visual recovery following intravenous tocilizumab in glucocorticoid resistant refractory giant cell arteritis"],"prefix":"10.1136","volume":"12","author":[{"given":"Carl Richard","family":"Svasti-Salee","sequence":"first","affiliation":[{"name":"Ophthalmology, Luton and Dunstable University Hospital NHS Foundation Trust, Luton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan P","family":"Mollan","sequence":"additional","affiliation":[{"name":"Neuro-Ophthalmology Unit, Ophthalmology Department, University Hospitals Birmingham NHS Foundation 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