{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T16:14:53Z","timestamp":1764260093348,"version":"3.44.0"},"reference-count":26,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,7,9]]},"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:p>The ureter is an extremely rare site for small cell neuroendocrine carcinoma. We present a case of this disease in a patient who presented without urological symptoms. The multidisciplinary team proposed nephroureterectomy (if fit) or watchful waiting as management. After discussion with the patient a decision in favour of watchful waiting was made. We report her case including a review of the literature, and emphasise that although small cell neuroendocrine carcinomas can be very aggressive, they can remain asymptomatic.<\/jats:p>","DOI":"10.1136\/bcr-2019-229290","type":"journal-article","created":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T11:25:16Z","timestamp":1564658716000},"page":"e229290","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Incidental finding of a small cell neuroendocrine carcinoma of the ureter"],"prefix":"10.1136","volume":"12","author":[{"given":"Obinna","family":"Obi-Njoku","sequence":"first","affiliation":[{"name":"Urology, Wrexham Maelor Hospital, Wrexham, UK"},{"name":"Urology, Whittington Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3587-5339","authenticated-orcid":false,"given":"Chris","family":"Bell","sequence":"additional","affiliation":[{"name":"Urology, Wrexham Maelor Hospital, Wrexham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prashant Ravindran","family":"Menon","sequence":"additional","affiliation":[{"name":"Urology, Wrexham Maelor Hospital, Wrexham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iqbal","family":"Shergill","sequence":"additional","affiliation":[{"name":"Urology, Wrexham Maelor Hospital, Wrexham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,8,1]]},"reference":[{"key":"2025082804254565000_12.7.e229290.1","doi-asserted-by":"crossref","first-page":"714","DOI":"10.5858\/arpa.2015-0106-RS","article-title":"Primary neuroendocrine tumors of the ureter: a short review","volume":"140","author":"Acosta","year":"2016","journal-title":"Arch Pathol Lab Med"},{"key":"2025082804254565000_12.7.e229290.2","doi-asserted-by":"publisher","DOI":"10.1177\/1066896915594882"},{"key":"2025082804254565000_12.7.e229290.3","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000011113","article-title":"Primary small cell carcinoma of the ureter: case report and review of the literature","volume":"97","author":"Farci","year":"2018","journal-title":"Medicine"},{"key":"2025082804254565000_12.7.e229290.4","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1089\/cren.2016.0103","article-title":"Neuroendocrine Tumor of the Ureter: A Zebra Among Horses","volume":"2","author":"Sood","year":"2016","journal-title":"J Endourol Case Rep"},{"key":"2025082804254565000_12.7.e229290.5","doi-asserted-by":"crossref","first-page":"257","DOI":"10.3892\/ol.2015.3899","article-title":"Neuroendocrine carcinoma of the ureter: A case report and literature review","volume":"11","author":"Wang","year":"2016","journal-title":"Oncol Lett"},{"key":"2025082804254565000_12.7.e229290.6","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.canrad.2015.07.155","article-title":"[Small cell neuroendocrine carcinoma of the upper urinary tract: A case report]","volume":"20","author":"Beddok","year":"2016","journal-title":"Cancer Radiother"},{"key":"2025082804254565000_12.7.e229290.7","doi-asserted-by":"crossref","first-page":"728","DOI":"10.3892\/ol.2013.1757","article-title":"Small cell neuroendocrine carcinoma of the ureter: A case report and literature review","volume":"7","author":"Ping","year":"2014","journal-title":"Oncol Lett"},{"key":"2025082804254565000_12.7.e229290.8","first-page":"729","article-title":"Primary large cell neuroendocrine carcinoma of the ureter","volume":"6","author":"Oshiro","year":"2013","journal-title":"Int J Clin Exp Pathol"},{"key":"2025082804254565000_12.7.e229290.9","doi-asserted-by":"publisher","DOI":"10.4103\/0970-1591.44273"},{"key":"2025082804254565000_12.7.e229290.10","first-page":"1","article-title":"An unexpected case of small cell neuroendocrine carcinoma of the ureter","volume":"3","author":"Vollstedt","year":"2018","journal-title":"Clin Surg"},{"key":"2025082804254565000_12.7.e229290.11","first-page":"26","article-title":"A retrospective immunohistochemical and clinicopathological study of small cell carcinomas of the urinary tract","volume":"26","author":"Chuang","year":"2003","journal-title":"Chang Gung Med J"},{"key":"2025082804254565000_12.7.e229290.12","first-page":"123","article-title":"[Urothelial carcinoma of ureter with neuroendocrine differentiation: a case report]","volume":"54","author":"Sakuma","year":"2008","journal-title":"Hinyokika Kiyo"},{"key":"2025082804254565000_12.7.e229290.13","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3182a0218f"},{"key":"2025082804254565000_12.7.e229290.14","first-page":"747","article-title":"[Clinical and pathologic characteristics of small cell neuroendocrine carcinoma of urinary tract]","volume":"41","author":"Guo","year":"2012","journal-title":"Zhonghua Bing Li Xue Za Zhi"},{"key":"2025082804254565000_12.7.e229290.15","first-page":"590","article-title":"Extrapulmonary small cell carcinoma--a medical center\u2019s experience","volume":"29","author":"Huang","year":"2006","journal-title":"Chang Gung Med J"},{"key":"2025082804254565000_12.7.e229290.16","doi-asserted-by":"publisher","DOI":"10.1080\/02841860601071893"},{"key":"2025082804254565000_12.7.e229290.17","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19970501)79:9<1729::AID-CNCR14>3.0.CO;2-#"},{"key":"2025082804254565000_12.7.e229290.18","doi-asserted-by":"crossref","first-page":"2262","DOI":"10.1002\/cncr.22235","article-title":"Extrapulmonary small cell cancer: a Canadian province\u2019s experience","volume":"107","author":"Haider","year":"2006","journal-title":"Cancer"},{"key":"2025082804254565000_12.7.e229290.19","first-page":"68","article-title":"Neuroendocrine carcinoma of the prostate gland","volume":"29","author":"Hoof","year":"2016","journal-title":"Proc"},{"key":"2025082804254565000_12.7.e229290.20","doi-asserted-by":"crossref","unstructured":"Tu X , Chang T , Nie L , et al . Large cell neuroendocrine carcinoma of the prostate: a systematic review and pooled analysis. Urol Int 2019:1\u20138.doi:10.1159\/000499883","DOI":"10.1159\/000499883"},{"key":"2025082804254565000_12.7.e229290.21","doi-asserted-by":"crossref","first-page":"291","DOI":"10.4103\/aja.aja_128_18","article-title":"Neuroendocrine cells of prostate cancer: biologic functions and molecular mechanisms","volume":"21","author":"Huang","year":"2019","journal-title":"Asian J Androl"},{"key":"2025082804254565000_12.7.e229290.22","doi-asserted-by":"publisher","DOI":"10.1158\/1541-7786.MCR-18-1101"},{"key":"2025082804254565000_12.7.e229290.23","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aav0891"},{"key":"2025082804254565000_12.7.e229290.24","doi-asserted-by":"crossref","first-page":"534","DOI":"10.3389\/fonc.2018.00534","article-title":"Co-occurrence of dermatomyositis and polycythemia unveiling rare de Novo neuroendocrine prostate tumor","volume":"8","author":"Papagoras","year":"2018","journal-title":"Front Oncol"},{"key":"2025082804254565000_12.7.e229290.25","doi-asserted-by":"crossref","first-page":"17","DOI":"10.18632\/oncotarget.26523","article-title":"Clinical characteristics, treatment outcomes and potential novel therapeutic options for patients with neuroendocrine carcinoma of the prostate","volume":"10","author":"Apostolidis","year":"2019","journal-title":"Oncotarget"},{"key":"2025082804254565000_12.7.e229290.26","first-page":"273","article-title":"Neuroendocrine differentiation of prostate cancer: a review","volume":"2","author":"Parimi","year":"2014","journal-title":"Am J Clin Exp Urol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2019-229290","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T11:26:58Z","timestamp":1756380418000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2019-229290"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":26,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2019,8,1]]},"published-print":{"date-parts":[[2019,7]]}},"alternative-id":["10.1136\/bcr-2019-229290"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2019-229290","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2019,7]]}}}