{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T20:40:03Z","timestamp":1756327203993,"version":"3.44.0"},"reference-count":9,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,5,13]]},"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:p>Ciguatera is a common but underreported tropical disease caused by the consumption of coral reef fish contaminated by ciguatoxins. Gastrointestinal and neurological symptoms predominate, but may be accompanied by cardiovascular features such as hypotension and sinus bradycardia. Here, we report an unusual case of junctional bradycardia caused by ciguatera in the Caribbean; to our knowledge, the first such report from the region. An increase in global sea temperatures is predicted to lead to the spread of ciguatera beyond traditional endemic areas, and the globalisation of trade in coral reef fish has resulted in sporadic cases occurring in developed countries far away from endemic areas. This case serves as a reminder to consider environmental intoxications such as ciguatera within the differential diagnosis of bradycardias.<\/jats:p>","DOI":"10.1136\/bcr-2019-229354","type":"journal-article","created":{"date-parts":[[2019,5,31]],"date-time":"2019-05-31T08:15:32Z","timestamp":1559290532000},"page":"e229354","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Junctional bradycardia caused by ciguatera intoxication"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6099-0948","authenticated-orcid":false,"given":"Rajendra","family":"Raman","sequence":"first","affiliation":[{"name":"Accident and Emergency, NHS Fife, Kirkcaldy, UK"},{"name":"Emergency Department, Dr Horacio E Oduber Hospital, Oranjestad, Aruba"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Coppes","sequence":"additional","affiliation":[{"name":"Emergency Department, Dr Horacio E Oduber Hospital, Oranjestad, Aruba"},{"name":"Emergency Department, Spaarne Gasthuis, Haarlem, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tessa","family":"Hellingman","sequence":"additional","affiliation":[{"name":"Emergency Department, Dr Horacio E Oduber Hospital, Oranjestad, Aruba"},{"name":"VU medisch centrum School of Medical Sciences, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Casper","family":"Lacl\u00e9","sequence":"additional","affiliation":[{"name":"Emergency Department, Dr Horacio E Oduber Hospital, Oranjestad, Aruba"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,5,30]]},"reference":[{"key":"2025082713252346000_12.5.e229354.1","doi-asserted-by":"crossref","unstructured":"Heimann K , Sparrow L . 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