{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:40:03Z","timestamp":1756305603938,"version":"3.44.0"},"reference-count":26,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,5,24]]},"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:p>Essential thrombocythaemia (ET) is characterised by elevated platelet count by a clonal stem cell disorder of megakaryocytes. Although thrombosis is a common complication of ET, splenic infarction (SI) is extremely rare. Here, we present the case of a 31-year-old Japanese man who presented with sudden-onset severe pain at the left hypochondrium on the day before admission. Enhanced abdominal CT revealed SI. The laboratory test results revealed a normal platelet count (439\u00d710<jats:sup>9<\/jats:sup>\/L). Subsequently, the patient was diagnosed with ET because the platelet count gradually increased to 50.0\u00d710<jats:sup>4<\/jats:sup>\/\u03bcL, and <jats:italic>JAK2 V617F<\/jats:italic> mutation was identified. Accordingly, low-dose aspirin was initiated, and no thrombotic episode occurred. Nevertheless, 6\u2009months postdischarge, the platelet count gradually increased to &gt;650 \u00d7 10<jats:sup>9<\/jats:sup>\/L, and anagrelide was initiated. This case demonstrates an unusual complication of acute SI due to ET under the rare situation of the normal platelet count.<\/jats:p>","DOI":"10.1136\/bcr-2019-229387","type":"journal-article","created":{"date-parts":[[2019,7,4]],"date-time":"2019-07-04T10:47:35Z","timestamp":1562237255000},"page":"e229387","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Acute splenic infarction presenting as an unusual manifestation of essential thrombocythaemia with normal platelet count"],"prefix":"10.1136","volume":"12","author":[{"given":"Katsuyuki","family":"Yoshida","sequence":"first","affiliation":[{"name":"Division of General Medicine, Department of Comprehensive Medicine 1, Jichi Ika Daigaku Fuzoku Saitama Iryo Center, Saitama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibuki","family":"Kurihara","sequence":"additional","affiliation":[{"name":"Division of General Medicine, Department of 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