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Often, the syndrome is marked by an insidious course during which patients present with generalised bony pain and weakness, which do not resolve until the underlying tumour is identified and treated. We present a case of a patient with Parkinson\u2019s disease whose subacute weakness, lower extremity paresis, and renal phosphate wasting led to the synchronous diagnosis of metastatic prostate adenocarcinoma and TIO.<\/jats:p>","DOI":"10.1136\/bcr-2019-229434","type":"journal-article","created":{"date-parts":[[2019,7,17]],"date-time":"2019-07-17T05:54:05Z","timestamp":1563342845000},"page":"e229434","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":11,"title":["Metastatic prostate cancer presenting as tumour-induced osteomalacia"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9815-1445","authenticated-orcid":false,"given":"Awo Akosua K","family":"Layman","sequence":"first","affiliation":[{"name":"Perelman School of Medicine, Medical Scientist Training Program, University of Pennsylvania, Philadelphia, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shivam","family":"Joshi","sequence":"additional","affiliation":[{"name":"Internal Medicine, New York University, New York, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjeev","family":"Shah","sequence":"additional","affiliation":[{"name":"Renal, Electrolyte, and Hypertension Division, University of Pennsylvania, Philadelphia, Pennsylvania, USA"},{"name":"Medicine, Corporal Michael J Crescenz VA Medical Center, Philadelphia, Pennsylvania, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,7,16]]},"reference":[{"key":"2025082712350962000_12.7.e229434.1","doi-asserted-by":"publisher","DOI":"10.1210\/er.2005-0019"},{"key":"2025082712350962000_12.7.e229434.2","doi-asserted-by":"crossref","unstructured":"He Q , Xu Z , Zhang B , et al . 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