{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T10:36:14Z","timestamp":1756463774061,"version":"3.44.0"},"reference-count":11,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,6,20]]},"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:p>\n                  <jats:italic>Leiomyomatosis peritonealis disseminata<\/jats:italic> (LPD) is a rare condition, characterised by the proliferation of peritoneal smooth muscle nodules. LPD is a benign disease with a low rate of malignant degeneration. We describe the case of a 46-year-old, asymptomatic, woman presenting with a mass on the left renal hilum, identified by ultrasound. A CT scan showed three nodules near the left kidney, a mass anterior to the vena cava and bilateral iliac nodules. Biopsy revealed a mesenchymal low-grade tumour. The patient underwent a left nephrectomy and excision of the other masses. The histological diagnosis revealed smooth muscle nodular proliferation with no malignant features, compatible with LPD. The differential diagnosis between LPD and metastatic leiomyosarcoma is sometimes very difficult because they are clinically very similar and even on histology the diagnosis can be tricky. Treatment is conservative in most cases, with surgical excision reserved for high-risk patients.<\/jats:p>","DOI":"10.1136\/bcr-2019-229564","type":"journal-article","created":{"date-parts":[[2019,7,9]],"date-time":"2019-07-09T06:09:10Z","timestamp":1562652550000},"page":"e229564","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Leiomyomatosis peritonealis disseminata: a rare disease with a difficult diagnosis"],"prefix":"10.1136","volume":"12","author":[{"given":"Daniel","family":"Martins Jord\u00e3o","sequence":"first","affiliation":[{"name":"Servi\u00e7o de Cirurgia Geral, Instituto Portugues de Oncologia de Coimbra Francisco Gentil EPE, Coimbra, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o","family":"Santos Pereira","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Cirurgia Geral, Instituto Portugues de Oncologia de Coimbra Francisco Gentil EPE, Coimbra, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuel","family":"Furtado","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Cirurgia Geral, Centro Hospitalar e Universitario de Coimbra EPE Coimbra Portugal, Coimbra, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel Cristina","family":"Ferr\u00e3o","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Cirurgia Geral, Instituto Portugues de Oncologia de Coimbra Francisco Gentil EPE, Coimbra, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,7,8]]},"reference":[{"key":"2025082711315279000_12.7.e229564.1","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.ijscr.2017.09.016","article-title":"Leiomyomatosis peritonealis disseminata: A case report and meticulous review of the literature","volume":"40","author":"Psathas","year":"2017","journal-title":"Int J Surg Case Rep"},{"key":"2025082711315279000_12.7.e229564.2","doi-asserted-by":"crossref","first-page":"315","DOI":"10.18295\/2075-0528.2807","article-title":"Leiomyomatosis Peritonealis Disseminata with Features of Carcinomatosis on Laparoscopy: A case report","volume":"9","author":"Al-Talib","year":"2009","journal-title":"Sultan Qaboos Univ Med J"},{"key":"2025082711315279000_12.7.e229564.3","doi-asserted-by":"crossref","first-page":"957","DOI":"10.3892\/mco.2016.848","article-title":"Leiomyomatosis peritonealis disseminata: A case report and review of the literature","volume":"4","author":"Wu","year":"2016","journal-title":"Mol Clin Oncol"},{"key":"2025082711315279000_12.7.e229564.4","doi-asserted-by":"crossref","first-page":"CCRep.S9530","DOI":"10.4137\/CCRep.S9530","article-title":"Leiomyomatosis peritonealis disseminata associated with endometriosis and multiple uterus-like mass: report of two cases","volume":"5","author":"Carvalho","year":"2012","journal-title":"Clin Med Insights Case Rep"},{"key":"2025082711315279000_12.7.e229564.5","doi-asserted-by":"crossref","first-page":"717","DOI":"10.3892\/ol.2014.2741","article-title":"Leiomyomatosis peritonealis disseminata associated with endometriosis: A case report and review of the literature","volume":"9","author":"Yang","year":"2015","journal-title":"Oncol Lett"},{"key":"2025082711315279000_12.7.e229564.6","first-page":"1","article-title":"A Rare Concurrence of Leiomyomatosis Peritonealis Disseminata, Leiomyosarcoma of the Pelvis and Leiomyomatous Nodule of the Liver","volume":"2016","author":"Tun","year":"2016","journal-title":"Case Rep Oncol Med"},{"key":"2025082711315279000_12.7.e229564.7","first-page":"204","article-title":"Multiple peritoneal leiomyomas associated with a granulose-cell tumor of the ovary, Am","volume":"64","author":"Wilson","year":"1952","journal-title":"J. Obstetr. Gynecol"},{"key":"2025082711315279000_12.7.e229564.8","unstructured":"Vilela F , Edral A , Martins R . Leiomiomatose peritoneal disseminada: uma condi\u00e7\u00e3o rara. Acta Obstretrica Ginecol\u00f3gica Portuguesa, 2017;11."},{"key":"2025082711315279000_12.7.e229564.9","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/s00404-009-1074-4","article-title":"Leiomyomatosis peritonealis disseminata in a pregnant woman","volume":"281","author":"Summa","year":"2010","journal-title":"Arch Gynecol Obstet"},{"key":"2025082711315279000_12.7.e229564.10","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.diii.2013.07.007","article-title":"Diffuse abdominopelvic leiomyomatosis: CT and MR imaging findings with histopathological correlation","volume":"95","author":"Thiry","year":"2014","journal-title":"Diagn Interv Imaging"},{"key":"2025082711315279000_12.7.e229564.11","doi-asserted-by":"publisher","DOI":"10.1159\/000178761"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2019-229564","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T18:32:00Z","timestamp":1756319520000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2019-229564"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":11,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2019,7,8]]},"published-print":{"date-parts":[[2019,7]]}},"alternative-id":["10.1136\/bcr-2019-229564"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2019-229564","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2019,7]]}}}