{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T21:54:29Z","timestamp":1773525269173,"version":"3.50.1"},"reference-count":10,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,7,9]]},"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:p>Takotsubo cardiomyopathy (TTC) is most commonly characterised by transient apical ballooning in response to physical or emotional stress without significant coronary artery disease (CAD). Various physical and emotional factors can trigger TTC. We report a case of hypothermia-induced biventricular TTC in an 84-year-old man admitted with a core body temperature of 29.8\u00b0C, followed by quick recovery of systolic function and resolution of wall motion abnormality after discharge. TTC should be suspected in hypothermic patients presenting with evidence of new onset heart failure and be added to the expanding list of factors triggering TTC. Similar to TTC induced by various other factors, hypothermia-induced TTC also carries a favourable prognosis with relatively quick recovery of wall motion abnormalities.<\/jats:p>","DOI":"10.1136\/bcr-2019-229761","type":"journal-article","created":{"date-parts":[[2019,7,27]],"date-time":"2019-07-27T11:46:09Z","timestamp":1564227969000},"page":"e229761","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Hypothermia-triggered biventricular Takotsubo cardiomyopathy: the octopus that survived the polar vortex"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2991-8689","authenticated-orcid":false,"given":"Mustafa","family":"Ajam","sequence":"first","affiliation":[{"name":"Internal Medicine, Detroit Medical Center, Detroit, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Shokr","sequence":"additional","affiliation":[{"name":"Internal Medicine, Wayne State University, Detroit Medical Center, Detroit, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Firas","family":"Ajam","sequence":"additional","affiliation":[{"name":"Internal Medicine, Jersey Shore University Medical Center, Neptune City, New Jersey, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Afonso","sequence":"additional","affiliation":[{"name":"Internal Medicine, Wayne State University, Detroit Medical Center, Detroit, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,7,27]]},"reference":[{"key":"2025082712382138000_12.7.e229761.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2012.03.020"},{"key":"2025082712382138000_12.7.e229761.2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1406761"},{"key":"2025082712382138000_12.7.e229761.3","first-page":"305","article-title":"Biventricular Takotsubo cardiomyopathy: case study and review of literature","volume":"40","author":"Daoko","year":"2013","journal-title":"Tex Heart Inst J"},{"key":"2025082712382138000_12.7.e229761.4","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehl274"},{"key":"2025082712382138000_12.7.e229761.5","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2012-008143"},{"key":"2025082712382138000_12.7.e229761.6","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1007\/s00101-007-1219-4","article-title":"Hyperthermie und Hypothermie","volume":"56","author":"Deussen","year":"2007","journal-title":"Anaesthesist"},{"key":"2025082712382138000_12.7.e229761.7","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp149"},{"key":"2025082712382138000_12.7.e229761.8","doi-asserted-by":"crossref","first-page":"2032","DOI":"10.1093\/eurheartj\/ehy076","article-title":"International Expert Consensus Document on Takotsubo Syndrome (Part I): clinical characteristics, diagnostic criteria, and pathophysiology","volume":"39","author":"Ghadri","year":"2018","journal-title":"Eur Heart J"},{"key":"2025082712382138000_12.7.e229761.9","first-page":"192","article-title":"The evaluation and management of accidental hypothermia","volume":"49","author":"Kempainen","year":"2004","journal-title":"Respir Care"},{"key":"2025082712382138000_12.7.e229761.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.12.004"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2019-229761","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T19:38:27Z","timestamp":1756323507000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2019-229761"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":10,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2019,7,27]]},"published-print":{"date-parts":[[2019,7]]}},"alternative-id":["10.1136\/bcr-2019-229761"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2019-229761","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7]]}}}