{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T07:36:24Z","timestamp":1782804984414,"version":"3.54.5"},"reference-count":13,"publisher":"BMJ","issue":"9","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,8,28]]},"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:p>A 12-year-old boy presented with central chest pain, shortness of breath and type 1 respiratory failure. He had a background of graft versus host disease (GvHD), which was currently managed with imatinib therapy. A focused bedside ultrasound scan was performed revealing a large pericardial effusion. The child was referred to a tertiary paediatric cardiology centre where he underwent emergency pericardiocentesis, draining a total of 800 mL of pericardial fluid. Fluid analysis excluded infection, and with no other concerns for a GvHD flare the diagnosis of an imatinib-induced pericardial effusion was made. On terminating the therapy, the pericardial collection did not reaccumulate. Tyrosine kinase inhibitor-induced pericardial and\/or\u2009pleural effusion should be considered as a differential diagnosis in paediatric patients on this therapy presenting in a similar manner.<\/jats:p>","DOI":"10.1136\/bcr-2019-229975","type":"journal-article","created":{"date-parts":[[2019,9,11]],"date-time":"2019-09-11T08:45:19Z","timestamp":1568191519000},"page":"e229975","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Imatinib-induced pericardial effusion in a child"],"prefix":"10.1136","volume":"12","author":[{"given":"Charlotte","family":"Terry","sequence":"first","affiliation":[{"name":"Paediatrics, Croydon Health Services NHS Trust, Croydon, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascale","family":"Avery","sequence":"additional","affiliation":[{"name":"Emergency Department, Croydon Health Services NHS Trust, Croydon, 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