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Despite the treatment, there were two episodes of severe abdominal pain with peritonitis within a week. Perforation of descending colon and severe ischaemia of the ascending colon was observed during each emergency laparotomy, and ileostomy was performed. Vasculitis in the small vessels was confirmed. In conclusion, patient with severe intestinal involvement and who was unresponsive to conventional therapy was treated with surgery followed by rituximab administration, and remission was achieved.<\/jats:p>","DOI":"10.1136\/bcr-2019-230355","type":"journal-article","created":{"date-parts":[[2019,8,10]],"date-time":"2019-08-10T13:05:17Z","timestamp":1565442317000},"page":"e230355","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Granulomatosis with polyangiitis with intestinal involvement successfully treated with rituximab and surgery"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1358-1513","authenticated-orcid":false,"given":"Hitoshi","family":"Sato","sequence":"first","affiliation":[{"name":"Internal Medicine, South Miyagi Medical Center, Ogawara, 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