{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:02:29Z","timestamp":1787061749048,"version":"build-2736575974"},"reference-count":16,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,5,25]]},"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:p>\n                    A rare case of acquired amegakaryocytic thrombocytopenia (AATP) in a 35-year-old woman who presented with anaemia and thrombocytopenia at 22\u2009weeks gestation. The first diagnostic impression was of an evolving aplastic anaemia; however, the patient was simultaneously diagnosed with severe vitamin B\n                    <jats:sub>12<\/jats:sub>\n                    deficiency in the setting of vegetarianism. Once the cyanocobalamin deficiency was corrected, a repeat bone marrow biopsy revealed an isolated depletion of megakaryocytes, which suggested the diagnosis of AATP. Supportive care was provided for her anaemia and thrombocytopenia and she delivered a healthy baby girl with a normal platelet count. The patient was subsequently started on romiplostim with steady improvement in her platelet counts. This rare AATP case presentation highlights the importance of a well-structured diagnostic approach to thrombocytopenia during pregnancy and supports the successful use of thrombopoietin agonists for the management of AATP.\n                  <\/jats:p>","DOI":"10.1136\/bcr-2019-230361","type":"journal-article","created":{"date-parts":[[2019,6,22]],"date-time":"2019-06-22T05:55:31Z","timestamp":1561182931000},"page":"e230361","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Acquired amegakaryocytic thrombocytopenia as a rare cause of thrombocytopenia during pregnancy"],"prefix":"10.1136","volume":"12","author":[{"given":"Brittney S","family":"Zimmerman","sequence":"first","affiliation":[{"name":"Department of Hematology Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bridget","family":"Marcellino","sequence":"additional","affiliation":[{"name":"Department of Hematology Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siraj M","family":"El Jamal","sequence":"additional","affiliation":[{"name":"Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne S","family":"Renteria","sequence":"additional","affiliation":[{"name":"Hematology Oncology - 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