{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T09:40:01Z","timestamp":1756287601174,"version":"3.44.0"},"reference-count":6,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,8,28]]},"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:p>We report a case of a man aged 35\u2009years who presented with the chief complaint of painless diminution of vision in the right eye for 4\u2009months. Examination revealed a large inferior retinochoroidal mass along with retinal detachment. An anterior choroidal mass with moderate internal reflectivity was seen on B-scan ocular ultrasonography and MRI and CT scan were indicative of a mitotic aetiology. Fluorodeoxyglucose-positron emission tomography scan ruled out any other systemic foci of involvement. Based on the above findings, a provisional diagnosis of amelanotic choroidal melanoma was made and he was taken up for choroidal aspiration biopsy, wherein the cytopathology report revealed hypercellularity with no identifiable pigments. In view of the above, a diagnosticandtherapeutic enucleation was performed; however, the histopathology report of the enucleated specimen revealed poorly differentiated retinoblastoma. This case highlights that the diagnosis of retinoblastoma should be kept in mind even in adult patients.<\/jats:p>","DOI":"10.1136\/bcr-2019-230537","type":"journal-article","created":{"date-parts":[[2019,10,14]],"date-time":"2019-10-14T05:35:11Z","timestamp":1571031311000},"page":"e230537","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Retinoblastoma in an adult: a diagnostic dilemma"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0325-6461","authenticated-orcid":false,"given":"Ritika","family":"Mukhija","sequence":"first","affiliation":[{"name":"Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neiwete","family":"Lomi","sequence":"additional","affiliation":[{"name":"Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saumya","family":"Kumar","sequence":"additional","affiliation":[{"name":"Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seema","family":"Sen","sequence":"additional","affiliation":[{"name":"Ocular Pathology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,10,13]]},"reference":[{"key":"2025082702082425000_12.10.e230537.1","unstructured":"Petersen R . Retinoblastoma: Diagnosis and nonradiation therapies. Principles and practice of ophthalmology. Philadelphia: WB Saunders Co, 1994:3279\u201382."},{"key":"2025082702082425000_12.10.e230537.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(86)33629-7"},{"key":"2025082702082425000_12.10.e230537.3","doi-asserted-by":"crossref","first-page":"485","DOI":"10.4103\/0301-4738.190099","article-title":"Adult onset retinoblastoma","volume":"64","author":"Sengupta","year":"2016","journal-title":"Indian J Ophthalmol"},{"key":"2025082702082425000_12.10.e230537.4","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/S0039-6257(99)00132-0","article-title":"Retinoblastoma in adults. Report of three cases and review of the literature","volume":"44","author":"Biswas","year":"2000","journal-title":"Surv Ophthalmol"},{"key":"2025082702082425000_12.10.e230537.5","doi-asserted-by":"crossref","first-page":"2483","DOI":"10.1097\/IAE.0000000000000612","article-title":"Newly diagnosed active retinoblastoma in adults","volume":"35","author":"Kaliki","year":"2015","journal-title":"Retina"},{"key":"2025082702082425000_12.10.e230537.6","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1996.01100140602013"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2019-230537","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T09:08:33Z","timestamp":1756285713000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2019-230537"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":6,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2019,10,13]]},"published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1136\/bcr-2019-230537"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2019-230537","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2019,10]]}}}