{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T12:28:53Z","timestamp":1766492933834,"version":"3.44.0"},"reference-count":12,"publisher":"BMJ","issue":"12","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,11,23]]},"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:p>Digital dry gangrene is commonly seen in cases of connective tissue disease such as systemic sclerosis. In systemic lupus erythematosus (SLE) digital gangrene is rare. As initial manifestation, it is again a rare phenomenon because it occurs late in the course of disease. Here we are reporting the case of a woman who was having extensive cutaneous gangrene of her fingers and toes, as a first and foremost presentation without any other typical signs and symptoms of SLE. Her serology was positive for SLE. The patient was treated conservatively and responded well.<\/jats:p>","DOI":"10.1136\/bcr-2019-230869","type":"journal-article","created":{"date-parts":[[2019,12,9]],"date-time":"2019-12-09T04:45:47Z","timestamp":1575866747000},"page":"e230869","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["Digital dry gangrene as a primary manifestation of systemic lupus erythematosus"],"prefix":"10.1136","volume":"12","author":[{"given":"Satyendra Kumar","family":"Sonkar","sequence":"first","affiliation":[{"name":"Medicine, King George's Medical University, Lucknow, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satish","family":"Kumar","sequence":"additional","affiliation":[{"name":"Medicine, King George's Medical University, Lucknow, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virendra","family":"Atam","sequence":"additional","affiliation":[{"name":"Medicine, King George's Medical University, Lucknow, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shyam Chand","family":"Chaudhary","sequence":"additional","affiliation":[{"name":"Medicine, King George's Medical University, Lucknow, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,12,8]]},"reference":[{"key":"2025082708203334000_12.12.e230869.1","doi-asserted-by":"crossref","unstructured":"Adelowo O , Olaosebikan H , Ajani W , et al . Digital gangrene as the initial presentation of systemic lupus erythematosus. BMJ Case Rep 2012;2012. doi:doi:10.1136\/bcr-2012-006259. [Epub ahead of print: 01 Nov 2012].","DOI":"10.1136\/bcr-2012-006259"},{"key":"2025082708203334000_12.12.e230869.2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1962.03050310006002"},{"key":"2025082708203334000_12.12.e230869.3","doi-asserted-by":"crossref","first-page":"907","DOI":"10.7326\/0003-4819-62-5-907","article-title":"Peripheral vascular syndromes associated with systemic lupus erythematosus","volume":"62","author":"Alarcon-Segovia","year":"1965","journal-title":"Ann Intern Med"},{"key":"2025082708203334000_12.12.e230869.4","first-page":"100","article-title":"Small vessel vasculitis, an uncommon presentation of systemic lupus erythematosus","volume":"65","author":"Das","year":"2017","journal-title":"J Assoc Physicians India"},{"key":"2025082708203334000_12.12.e230869.5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2018\/1794723","article-title":"Severe preeclampsia, antiphospholipid syndrome, and ulnar artery thrombosis in a teenage pregnancy: a rare association","volume":"2018","author":"Patabendige","year":"2018","journal-title":"Case Rep Obstet Gynecol"},{"key":"2025082708203334000_12.12.e230869.6","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.50.4617"},{"key":"2025082708203334000_12.12.e230869.7","first-page":"335","article-title":"Digital gangrene in systemic lupus erythematosus","volume":"44","author":"Kurnia","year":"2012","journal-title":"Acta Med Indones"},{"key":"2025082708203334000_12.12.e230869.8","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.120123"},{"key":"2025082708203334000_12.12.e230869.9","doi-asserted-by":"publisher","DOI":"10.1177\/0961203309106643"},{"key":"2025082708203334000_12.12.e230869.10","doi-asserted-by":"crossref","first-page":"337","DOI":"10.12659\/AJCR.889290","article-title":"Peripheral gangrene: a rare presentation of systemic lupus erythematosus in a child","volume":"14","author":"Ziaee","year":"2013","journal-title":"Am J Case Rep"},{"key":"2025082708203334000_12.12.e230869.11","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ken210"},{"key":"2025082708203334000_12.12.e230869.12","doi-asserted-by":"crossref","unstructured":"K\u00fc\u00e7\u00fck\u015fahin O , D\u00fczg\u00fcn N , Okoh AK , et al . Response to rituximab in a case of lupus associated digital ischemia. Case Rep Rheumatol 2014;2014.doi:10.1155\/2014\/763608","DOI":"10.1155\/2014\/763608"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2019-230869","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T15:20:38Z","timestamp":1756308038000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2019-230869"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":12,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2019,12,8]]},"published-print":{"date-parts":[[2019,12]]}},"alternative-id":["10.1136\/bcr-2019-230869"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2019-230869","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2019,12]]}}}