{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T11:10:21Z","timestamp":1756379421030,"version":"3.44.0"},"reference-count":12,"publisher":"BMJ","issue":"12","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,11,27]]},"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:p>\n                  <jats:italic>Erysipelothrix Rhusiopathiae<\/jats:italic> is a Gram-positive bacillus that is ubiquitous in nature. The bacterium is a zoonotic pathogen known to infect wild and domestic animals. Human infections, however, are uncommon and typically present with localised or generalised cutaneous lesions. Systemic infection in the form of bacteraemia with seeding to various organs is the least common form of the disease. Infections in humans tend to be associated with occupational exposure and close contact with animals. Clinical data of a 61-year-old male patient with Gram-positive bacilli bacteraemia and <jats:italic>E.<\/jats:italic>\n                  <jats:italic>Rh<\/jats:italic>\n                  <jats:italic>usiopathiae<\/jats:italic>-induced endocarditis are presented here. The patient presented with refractory congestive heart failure secondary to severe acute aortic regurgitation mandating surgical valve replacement. The described case has special clinical merit given the lack of fever and leukocytosis, absence of erysipeloid cutaneous manifestations and refractoriness to medical management. <jats:italic>E. Rhusiopathiae<\/jats:italic> should be considered in the differential diagnosis for Gram-positive bacilli bacteraemia and endocarditis. In the proper clinical setting, occupational exposure and animal contacts are helpful clues to raise suspicion for this bacillus. The high mortality associated with the pathogen should urge for early identification and initiation of antimicrobial treatment.<\/jats:p>","DOI":"10.1136\/bcr-2019-230891","type":"journal-article","created":{"date-parts":[[2019,12,20]],"date-time":"2019-12-20T04:55:12Z","timestamp":1576817712000},"page":"e230891","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Native valve endocarditis caused by <i>E<\/i>\n                  <i>rysipelothrix<\/i>\n                  <i>Rh<\/i>\n                  <i>usiopathiae<\/i>: presenting with refractory heart failure and requiring surgical valve replacement\u2014report on a rare zoonosis"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7518-5415","authenticated-orcid":false,"given":"Ahmed M","family":"Altibi","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Henry Ford Allegiance Health, Jackson, Michigan, USA"},{"name":"Harvard TH Chan School of Public Health, Harvard University, Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed","family":"Khalid","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Henry Ford Allegiance Health, Jackson, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivek","family":"Kak","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Henry Ford Allegiance Health, Jackson, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brijesh","family":"Patel","sequence":"additional","affiliation":[{"name":"Heart and Vascular Institute, West Virginia University, Morgantown, West Virginia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,12,19]]},"reference":[{"key":"2025082803331123000_12.12.e230891.1","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-48-9-789"},{"key":"2025082803331123000_12.12.e230891.2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.4739.1063"},{"key":"2025082803331123000_12.12.e230891.3","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/S1473-3099(10)70089-X","article-title":"Mandell, Douglas, and Bennett's principles and practice of infectious diseases","volume":"10","author":"Zumla","year":"2010","journal-title":"Lancet Infect Dis"},{"key":"2025082803331123000_12.12.e230891.4","doi-asserted-by":"crossref","DOI":"10.1016\/0002-9343(65)90203-2","article-title":"Subacute bacterial endocarditis due to Erysipelothrix rhusiopathiae. Report of a case and review of the literature","volume":"38","author":"Procter","year":"1965","journal-title":"Am J Med"},{"key":"2025082803331123000_12.12.e230891.5","first-page":"196","article-title":"[Cutaneous manifestations of erysipeloid septicemia]","volume":"125","author":"Clyti","year":"1998","journal-title":"Ann Dermatol Venereol"},{"key":"2025082803331123000_12.12.e230891.6","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/0002-9343(85)90295-5","article-title":"Erysipelothrix rhusiopathiae bacteremia presenting as septic shock","volume":"78","author":"Ognibene","year":"1985","journal-title":"Am J Med"},{"key":"2025082803331123000_12.12.e230891.7","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.60.3.434"},{"key":"2025082803331123000_12.12.e230891.8","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.idcr.2017.11.002","article-title":"First reported case of vertebral osteomyelitis due to Erysipelothrix rhusiopathiae","volume":"11","author":"Lorenz","year":"2018","journal-title":"IDCases"},{"key":"2025082803331123000_12.12.e230891.9","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/10.2.317"},{"key":"2025082803331123000_12.12.e230891.10","doi-asserted-by":"crossref","DOI":"10.1086\/431218","article-title":"Mandell, Douglas, and Bennett's principles and practice of infectious diseases, 6th edition","volume":"41","author":"Masci","year":"2005","journal-title":"Clin Infect Dis"},{"key":"2025082803331123000_12.12.e230891.11","first-page":"730","article-title":"Erysipelothrix rhusiopathiae-induced aortic valve endocarditis: case report and literature review","volume":"8","author":"Hua","year":"2015","journal-title":"Int J Clin Exp Med"},{"key":"2025082803331123000_12.12.e230891.12","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.059931-0"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2019-230891","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T10:33:20Z","timestamp":1756377200000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2019-230891"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":12,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2019,12,19]]},"published-print":{"date-parts":[[2019,12]]}},"alternative-id":["10.1136\/bcr-2019-230891"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2019-230891","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2019,12]]}}}