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We herein report a case of a jejunal mesenteric lymphangioma that was initially detected incidentally in an asymptomatic patient with a subsequent sudden increase in size with resulting surrounding mass effect after 9\u2009months and a spontaneous partial regression at surgical resection. Our case is the first reported case which outlines a period in the natural history and evolution of microcystic mesenteric lymphangioma, illustrating the sudden enlargement likely attributable to spontaneous and self-limiting haemorrhage and subsequent partial regression at surgical resection. We thenceforth propose a possible management algorithm for adult patients with mesenteric lymphangiomas.<\/jats:p>","DOI":"10.1136\/bcr-2019-231037","type":"journal-article","created":{"date-parts":[[2023,3,14]],"date-time":"2023-03-14T00:11:15Z","timestamp":1678752675000},"page":"e231037","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Spontaneous partial regression of a microcystic jejunal mesenteric lymphangioma and a proposed management algorithm"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3439-2597","authenticated-orcid":false,"given":"Dominic Ti Ming","family":"Tan","sequence":"first","affiliation":[{"name":"College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK"},{"name":"Department of Surgery, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aik Yong","family":"Chok","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Singapore General Hospital, Bukit Merah, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin Livingston","family":"Farah","sequence":"additional","affiliation":[{"name":"Division of Pathology, Department of Anatomical Pathology, Singapore General Hospital, Bukit Merah, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yet Yen","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Radiology, Changi General Hospital, 2 Simei Street 3, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ee-Lin","family":"Toh","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Singapore General Hospital, Bukit Merah, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,11,24]]},"reference":[{"key":"2025082701574841000_12.11.e231037.1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v17.i11.1515"},{"key":"2025082701574841000_12.11.e231037.2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v18.i43.6328"},{"key":"2025082701574841000_12.11.e231037.3","doi-asserted-by":"crossref","unstructured":"Khalid H , Osama A . 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