{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T16:10:01Z","timestamp":1756311001087,"version":"3.44.0"},"reference-count":14,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,7,14]]},"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:p>Hypoglycaemia in infants and children is caused by a number of endocrine and metabolic defects, some of which are unique to this age group. Growth hormone deficiency (GHD) has been rarely reported as a cause of recurrent fasting hypoglycaemia in children. An 18-month-old male child presented to us for evaluation of neuroglycopenic symptoms caused by recurrent episodes of fasting hypoglycaemia. Laboratory evaluation revealed ketotic hypoinsulinaemic hypoglycaemia. The child was diagnosed to have GHD on the basis of two failed stimulation tests. A detailed work-up for metabolic and other hormonal causes of hypoglycaemia was negative. We present the case for its rarity and to highlight the importance of a detailed metabolic and hormonal assessment in evaluation of childhood hypoglycaemia.<\/jats:p>","DOI":"10.1136\/bcr-2019-231056","type":"journal-article","created":{"date-parts":[[2019,7,27]],"date-time":"2019-07-27T11:46:47Z","timestamp":1564228007000},"page":"e231056","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Isolated growth hormone deficiency presenting with recurrent hypoglycaemia in a toddler"],"prefix":"10.1136","volume":"12","author":[{"given":"Hiya","family":"Boro","sequence":"first","affiliation":[{"name":"Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0922-5022","authenticated-orcid":false,"given":"Alpesh","family":"Goyal","sequence":"additional","affiliation":[{"name":"Endocrinology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajesh","family":"Khadgawat","sequence":"additional","affiliation":[{"name":"Endocrinology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,7,27]]},"reference":[{"key":"2025082708392583000_12.7.e231056.1","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1007\/s10654-018-0425-5","article-title":"Moderate neonatal hypoglycemia and adverse neurological development at 2-6\u00a0years of age","volume":"33","author":"Wickstr\u00f6m","year":"2018","journal-title":"Eur J Epidemiol"},{"key":"2025082708392583000_12.7.e231056.2","doi-asserted-by":"crossref","first-page":"408","DOI":"10.21037\/tp.2017.10.05","article-title":"Approach to hypoglycemia in infants and children","volume":"6","author":"Gandhi","year":"2017","journal-title":"Transl Pediatr"},{"key":"2025082708392583000_12.7.e231056.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2015.03.057"},{"key":"2025082708392583000_12.7.e231056.4","unstructured":"Sunehag A , Haymond MW . 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