{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T04:36:44Z","timestamp":1772080604751,"version":"3.50.1"},"reference-count":6,"publisher":"BMJ","issue":"9","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,8,24]]},"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:p>We present an unusual case of skull base osteomyelitis in an 88-year-old woman. She presented with gradual onset unilateral headache and diplopia. On examination, there was evidence of a left-sided Horner\u2019s and ipsilateral sixth nerve palsy. In addition to persistent raised inflammatory markers, an MRI neck identified signal change in the petrous bone confirming a diagnosis of skull base osteomyelitis. Skull base osteomyelitis should be considered in presentations of subacute raised inflammatory markers in the context of ipsilateral cranial nerve signs.<\/jats:p>","DOI":"10.1136\/bcr-2019-231062","type":"journal-article","created":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T07:25:21Z","timestamp":1568877921000},"page":"e231062","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Insidious onset of headache, diplopia and Horner\u2019s syndrome: a rare case of petrous bone osteomyelitis"],"prefix":"10.1136","volume":"12","author":[{"given":"Simon","family":"Biart","sequence":"first","affiliation":[{"name":"Acute Medicine, Arrowe Park Hospital, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janki","family":"Panicker","sequence":"additional","affiliation":[{"name":"Diabetes and Endocrine, Royal Liverpool and Broadgreen Hospitals NHS Trust, Liverpool, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,9,18]]},"reference":[{"key":"2025082703345440000_12.9.e231062.1","doi-asserted-by":"publisher","DOI":"10.1080\/00016480600818054"},{"key":"2025082703345440000_12.9.e231062.2","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.wneu.2017.12.066","article-title":"Cranial osteomyelitis: a comprehensive review of modern therapies","volume":"111","author":"Mortazavi","year":"2018","journal-title":"World Neurosurg"},{"key":"2025082703345440000_12.9.e231062.3","first-page":"255","article-title":"Skull base osteomyelitis presenting as Villaret\u2019s syndrome","volume":"15","author":"Huang","year":"2006","journal-title":"Acta Neurol Taiwan"},{"key":"2025082703345440000_12.9.e231062.4","doi-asserted-by":"publisher","DOI":"10.1136\/pmj.76.899.559"},{"key":"2025082703345440000_12.9.e231062.5","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(03)00858-2"},{"key":"2025082703345440000_12.9.e231062.6","unstructured":"Collins M , Colglazier R , Crowder R , et al . A 70-year-old man with uncontrolled type 2 diabetes, reported CVA with residual complete right facial paralysis, and recent mastoidectomy presents with chronic headache and asymmetry of oropharynx on exam. Am J Neuroradiol 2019."}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2019-231062","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:35:04Z","timestamp":1756290904000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2019-231062"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":6,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2019,9,18]]},"published-print":{"date-parts":[[2019,9]]}},"alternative-id":["10.1136\/bcr-2019-231062"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2019-231062","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9]]}}}