{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T05:00:32Z","timestamp":1768453232150,"version":"3.49.0"},"reference-count":8,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,9,11]]},"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:p>Menetrier disease is a rare disease characterised by hyperplasia of the gastric epithelium and large gastric folds. We present a case of a 58-year-old woman who was referred with iron deficiency anaemia, with a family history of a sibling who had undergone gastrectomy for presumed gastric malignancy. Endoscopy showed prominent gastric mucosal folds and biopsies showed hyperplastic gastric mucosa, with prominent foveolar hyperplasia suggestive of Menetrier disease. Further information about her brother\u2019s diagnosis was sought, and it was found that his pathology after gastrectomy showed diffuse glandular hyperplasia also in keeping with Menetrier disease. Adult familial Menetrier disease has so far been a rarity in the literature\u2014review elicits five previous cases of this presentation in siblings.<\/jats:p>","DOI":"10.1136\/bcr-2019-231175","type":"journal-article","created":{"date-parts":[[2019,10,23]],"date-time":"2019-10-23T15:36:07Z","timestamp":1571844967000},"page":"e231175","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Unusual case of adult familial Menetrier disease in siblings"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4855-1827","authenticated-orcid":false,"given":"Emily","family":"Brownson","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Queen Elizabeth University Hospital, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian J","family":"Stanley","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Glasgow Royal Infirmary, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prakash","family":"Konanahalli","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Queen Elizabeth University Hospital, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John P","family":"Seenan","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Queen Elizabeth University Hospital, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,10,23]]},"reference":[{"key":"2025082710001801000_12.10.e231175.1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.4132\/jptm.2015.09.15","article-title":"M\u00e9n\u00e9trier\u2019s Disease: Its Mimickers and Pathogenesis","volume":"50","author":"Huh","year":"2016","journal-title":"J Pathol Transl Med"},{"key":"2025082710001801000_12.10.e231175.2","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1097\/00042737-200304000-00019","article-title":"An unusual expression of hyperplastic gastropathy (Menetrier type) in twins","volume":"15","author":"Ibarrola","year":"2003","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"2025082710001801000_12.10.e231175.3","doi-asserted-by":"publisher","DOI":"10.1136\/gut.28.11.1517"},{"key":"2025082710001801000_12.10.e231175.4","first-page":"525","article-title":"Chronic hypertrophic gastritis. 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