{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:02:55Z","timestamp":1756425775289,"version":"3.44.0"},"reference-count":16,"publisher":"BMJ","issue":"11","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,10,26]]},"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:p>\n                  <jats:italic>Escherichia hermannii<\/jats:italic> is a rare monomicrobial cause of infection in humans. <jats:italic>E. hermannii<\/jats:italic> has never before been reported as the sole isolate from an infected open tibia fracture. We present a case of <jats:italic>E. hermannii<\/jats:italic> infection after a type III open tibia fracture. The patient was initially treated with irrigation and debridement, open reduction internal fixation and primary wound closure. However, after 8 weeks, he developed a draining wound and infection at the fracture site. He required a repeat debridement, hardware removal, external fixation and 6 weeks of intravenous ceftriaxone for treatment. At 2-year follow-up, he remains infection free, asymptomatic and continues to work with excellent functional outcomes. This case adds to the growing literature that evidences <jats:italic>E. hermannii<\/jats:italic> as an organism that can be pathogenic, virulent and cause monomicrobial infection.<\/jats:p>","DOI":"10.1136\/bcr-2019-231206","type":"journal-article","created":{"date-parts":[[2019,11,27]],"date-time":"2019-11-27T05:15:14Z","timestamp":1574831714000},"page":"e231206","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["<i>Escherichia hermannii<\/i> as the sole cause of osteomyelitis in a patient with an open tibial shaft fracture"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3306-7706","authenticated-orcid":false,"given":"Jocelyn","family":"Compton","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malynda","family":"Wynn","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael C","family":"Willey","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Poorani","family":"Sekar","sequence":"additional","affiliation":[{"name":"Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,11,26]]},"reference":[{"key":"2025082800492286000_12.11.e231206.1","doi-asserted-by":"crossref","first-page":"S21","DOI":"10.1097\/BOT.0000000000000667","article-title":"Infection after orthopaedic trauma: prevention and treatment","volume":"30 Suppl 3","author":"Yun","year":"2016","journal-title":"J Orthop Trauma"},{"key":"2025082800492286000_12.11.e231206.2","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0141973","article-title":"A systematic review and meta-analysis of Ilizarov methods in the treatment of infected nonunion of tibia and femur","volume":"10","author":"Yin","year":"2015","journal-title":"PLoS One"},{"key":"2025082800492286000_12.11.e231206.3","doi-asserted-by":"crossref","DOI":"10.2106\/JBJS.RVW.17.00197","article-title":"Antibiotic prophylaxis in the management of open fractures: a systematic survey of current practice and recommendations","volume":"7","author":"Chang","year":"2019","journal-title":"JBJS Rev"},{"key":"2025082800492286000_12.11.e231206.4","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1128\/jcm.15.4.703-713.1982","article-title":"Atypical biogroups of Escherichia coli found in clinical specimens and description of Escherichia hermannii sp. nov","volume":"15","author":"Brenner","year":"1982","journal-title":"J Clin Microbiol"},{"key":"2025082800492286000_12.11.e231206.5","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1128\/jcm.22.2.283-285.1985","article-title":"Colonization of human wounds by Escherichia vulneris and Escherichia hermannii","volume":"22","author":"Pien","year":"1985","journal-title":"J Clin Microbiol"},{"key":"2025082800492286000_12.11.e231206.6","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01119-08"},{"key":"2025082800492286000_12.11.e231206.7","doi-asserted-by":"crossref","first-page":"453","DOI":"10.2106\/00004623-197658040-00004","article-title":"Prevention of infection in the treatment of one thousand and twenty-five open fractures of long bones: retrospective and prospective analyses","volume":"58","author":"Gustilo","year":"1976","journal-title":"J Bone Joint Surg Am"},{"key":"2025082800492286000_12.11.e231206.8","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.nmni.2017.11.005","article-title":"Escherichia hermannii as the sole pathogen in urosepsis: case report","volume":"21","author":"Haasdijk","year":"2018","journal-title":"New Microbes and New Infections"},{"key":"2025082800492286000_12.11.e231206.9","doi-asserted-by":"crossref","DOI":"10.1097\/PAT.0b013e3283633fd7","article-title":"Escherichia hermannii bloodstream infection in a long-term haemodialysis patient","volume":"45","author":"Choudhury","year":"2013","journal-title":"Pathology"},{"key":"2025082800492286000_12.11.e231206.10","doi-asserted-by":"crossref","unstructured":"Ioannou P . Escherichia hermannii infections in humans: a systematic review. Tropical Medicine and Infectious Disease 2019;4.doi:10.3390\/tropicalmed4010017","DOI":"10.3390\/tropicalmed4010017"},{"key":"2025082800492286000_12.11.e231206.11","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00983-13"},{"key":"2025082800492286000_12.11.e231206.12","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1007\/s00068-015-0519-7","article-title":"Open distal tibial shaft fractures: a retrospective comparison of medial plate versus nail fixation","volume":"42","author":"Avilucea","year":"2016","journal-title":"Eur J Trauma Emerg Surg"},{"key":"2025082800492286000_12.11.e231206.13","doi-asserted-by":"publisher","DOI":"10.1097\/BOT.0b013e318213f709"},{"key":"2025082800492286000_12.11.e231206.14","doi-asserted-by":"crossref","first-page":"S90","DOI":"10.1016\/j.jcot.2017.07.001","article-title":"Soft tissue complications in distal tibial fractures managed with medial locking plates: a myth or reality?","volume":"8","author":"Jain","year":"2017","journal-title":"Journal of Clinical Orthopaedics and Trauma"},{"key":"2025082800492286000_12.11.e231206.15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2174\/1874285801610010001","article-title":"Catheter related Escherichia hermannii sepsis in a haemodialysis patient","volume":"10","author":"Rank","year":"2016","journal-title":"Open Microbiol J"},{"key":"2025082800492286000_12.11.e231206.16","doi-asserted-by":"publisher","DOI":"10.1177\/0954411914556137"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2019-231206","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:49:33Z","timestamp":1756367373000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2019-231206"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":16,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2019,11,26]]},"published-print":{"date-parts":[[2019,11]]}},"alternative-id":["10.1136\/bcr-2019-231206"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2019-231206","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2019,11]]}}}