{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:40:02Z","timestamp":1756374002785,"version":"3.44.0"},"reference-count":14,"publisher":"BMJ","issue":"9","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,9,8]]},"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:p>Brown tumours are rare osteolytic lesions that occur secondary to hyperparathyroidism (HPT). In 2% of all cases, the craniofacial bones are affected, most frequently the mandible. HPT is classified according to aetiology into three types, of which tertiary HPT is the rarest. Here we present the case of a 42-year-old man who had received a renal transplant 16 years previously and was referred due to swelling on the right side of his jaw. An orthopantomogram revealed a multilocular radiolucency in the right body of the mandible. The bony lesion was treated by surgical enucleation. After histopathological examination of the lesion, the diagnosis of brown tumour of the mandible secondary to tertiary HPT was reached. The patient\u2019s recovery was uneventful and follow-up radiography showed good bone healing.<\/jats:p>","DOI":"10.1136\/bcr-2019-231231","type":"journal-article","created":{"date-parts":[[2019,9,24]],"date-time":"2019-09-24T11:45:31Z","timestamp":1569325531000},"page":"e231231","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Rare brown tumour of the mandible secondary to tertiary hyperparathyroidism in a renal transplant recipient"],"prefix":"10.1136","volume":"12","author":[{"given":"Aur\u00e9lien M","family":"Gu\u00e9roult","sequence":"first","affiliation":[{"name":"Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malcolm","family":"Cameron","sequence":"additional","affiliation":[{"name":"Oral and Maxillofacial Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,9,24]]},"reference":[{"key":"2025082802041801000_12.9.e231231.1","doi-asserted-by":"crossref","first-page":"bcr-2017-220722","DOI":"10.1136\/bcr-2017-220722","article-title":"Giant mediastinal parathyroid adenoma presenting as bilateral brown tumour of mandible: a rare presentation of primary hyperparathyroidism","volume":"2017","author":"Talukder","year":"2017","journal-title":"BMJ Case Rep"},{"key":"2025082802041801000_12.9.e231231.2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00784-017-2124-0","article-title":"Systematic review of oral manifestations related to hyperparathyroidism","volume":"22","author":"Palla","year":"2018","journal-title":"Clin Oral Investig"},{"key":"2025082802041801000_12.9.e231231.3","doi-asserted-by":"publisher","DOI":"10.1148\/radiographics.19.5.g99se021107"},{"key":"2025082802041801000_12.9.e231231.4","first-page":"e10","article-title":"Multiple brown tumours of tertiary hyperparathyroidism in a renal transplant recipient: a case report","volume":"15","author":"Magalh\u00e3es","year":"2010","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"2025082802041801000_12.9.e231231.5","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1177\/014556130508400714","article-title":"Brown tumor of the facial bones: case report and literature review","volume":"84","author":"Lessa","year":"2005","journal-title":"Ear Nose Throat J"},{"key":"2025082802041801000_12.9.e231231.6","doi-asserted-by":"crossref","unstructured":"Nair PP , Gharote HP , Thomas S , et al . Brown tumour of the jaw. BMJ Case Rep 2011:4\u20137.","DOI":"10.1136\/bcr.07.2011.4465"},{"key":"2025082802041801000_12.9.e231231.7","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr\/88771381"},{"key":"2025082802041801000_12.9.e231231.8","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr\/81694583"},{"key":"2025082802041801000_12.9.e231231.9","doi-asserted-by":"crossref","first-page":"e19","DOI":"10.1016\/j.jcms.2011.01.001","article-title":"Unusually rapid growth of brown tumour in the mandible after parathyroidectomy associated with the presence of a supernumerary parathyroid gland","volume":"40","author":"Dorigatti de \u00c1vila","year":"2012","journal-title":"J Craniomaxillofac Surg"},{"key":"2025082802041801000_12.9.e231231.10","first-page":"543","article-title":"Highly aggressive brown tumor in the jaw associated with tertiary hyperparathyroidism","volume":"28","author":"Pinto","year":"2006","journal-title":"Pediatr Dent"},{"key":"2025082802041801000_12.9.e231231.11","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1097\/IOP.0b013e3181b8e3ec","article-title":"Orbital involvement in craniofacial brown tumors","volume":"26","author":"Cecchetti","year":"2010","journal-title":"Ophthalmic Plast Reconstr Surg"},{"key":"2025082802041801000_12.9.e231231.12","first-page":"1","article-title":"Oral consideration and dental management in organ transplant patient","volume":"2","author":"Kamala","year":"2010","journal-title":"J Int Oral Health"},{"key":"2025082802041801000_12.9.e231231.13","doi-asserted-by":"crossref","first-page":"459","DOI":"10.20471\/acc.2016.55.03.15","article-title":"Oral lesions in kidney transplant recipients","volume":"55","author":"Levarda-Hudolin","year":"2016","journal-title":"Acta Clin Croat"},{"key":"2025082802041801000_12.9.e231231.14","first-page":"127","article-title":"Clinical oral findings in dialysis and kidney-transplant patients","volume":"42","author":"Dirschnabel","year":"2011","journal-title":"Quintessence Int"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2019-231231","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:04:25Z","timestamp":1756371865000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2019-231231"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":14,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2019,9,24]]},"published-print":{"date-parts":[[2019,9]]}},"alternative-id":["10.1136\/bcr-2019-231231"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2019-231231","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2019,9]]}}}