{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T15:41:55Z","timestamp":1758814915058,"version":"3.44.0"},"reference-count":21,"publisher":"BMJ","issue":"12","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,12,4]]},"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:p>This case report describes the case of a 37-year-old man that noticed an intrascrotal right mass with 1\u2009month of evolution. During physical exam presented with a large mass at the inferior portion of the right testicle, clearly separated from the testicle, with a tender consistency and mobile. An ultrasound was performed that showed a solid and subcutaneous nodular lesion, extra testicular, heterogeneous, measuring 7.2\u2009cm. Pelvic magnetic resonance imageMRI showed a lesion compatible with a lipoma. The patient was subjected to surgical excision of the lesion by scrotal access, having histology revealed a lipoblastoma (LB) of the scrotum. Histological diagnosis was obtained by microscopic characteristics (well-circumscribed fatty neoplasm) and immunohistochemistry (stains for CD34, S100 protein and PLAG1 were positive; stains for MDM2 and CDK4 were negative). LB is extremely rare after adolescence in any location, being this first described case of intrascrotal LB described in adulthood.<\/jats:p>","DOI":"10.1136\/bcr-2019-231320","type":"journal-article","created":{"date-parts":[[2019,12,11]],"date-time":"2019-12-11T05:04:15Z","timestamp":1576040655000},"page":"e231320","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Intrascrotal lipoblastoma in adulthood"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9303-6245","authenticated-orcid":false,"given":"M\u00e1rio Jos\u00e9","family":"Pereira-Louren\u00e7o","sequence":"first","affiliation":[{"name":"Urology and Kidney Transplantation, Centro Hospitalar e Universit\u00e1rio de Coimbra EPE, Coimbra, Portugal"},{"name":"Urology, Instituto Portugu\u00eas de Oncologia de Coimbra Francisco Gentil EPE, Coimbra, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7960-774X","authenticated-orcid":false,"given":"Duarte","family":"Vieira-Brito","sequence":"additional","affiliation":[{"name":"Urology and Kidney Transplantation, Centro Hospitalar e Universit\u00e1rio de Coimbra EPE, Coimbra, Portugal"},{"name":"Urology, Instituto Portugu\u00eas de Oncologia de Coimbra Francisco Gentil EPE, Coimbra, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Pedro","family":"Peralta","sequence":"additional","affiliation":[{"name":"Urology, Instituto Portugu\u00eas de Oncologia de Coimbra Francisco Gentil EPE, Coimbra, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"No\u00e9mia","family":"Castelo-Branco","sequence":"additional","affiliation":[{"name":"Pathology, Instituto Portugu\u00eas de Oncologia de Coimbra Francisco Gentil EPE, Coimbra, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,12,10]]},"reference":[{"key":"2025082707084577000_12.12.e231320.1","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1007\/s00428-003-0799-x","article-title":"Lipoblastoma in a 23-year-old male: distinction from atypical lipomatous tumor using cytogenetic and fluorescence in-situ hybridization analysis","volume":"442","author":"Sciot","year":"2003","journal-title":"Virchows Arch"},{"key":"2025082707084577000_12.12.e231320.2","doi-asserted-by":"crossref","DOI":"10.1186\/s13104-018-3153-8","article-title":"Lipoblastoma: a clinicopathologic review of 23 cases from a major tertiary care center plus detailed review of literature","volume":"11","author":"Abdul-Ghafar","year":"2018","journal-title":"BMC Res Notes"},{"key":"2025082707084577000_12.12.e231320.3","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.humpath.2015.08.019","article-title":"Immunohistochemical expression of p16 in lipoblastomas","volume":"47","author":"Cappellesso","year":"2016","journal-title":"Hum Pathol"},{"key":"2025082707084577000_12.12.e231320.4","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/S0344-0338(99)80122-8","article-title":"Benign recurring lipoblastoma in an adult versus well differentiated subcutaneous myxoid liposarcoma: clinicopathologic, immunohistochemical and molecular analysis of a unique case","volume":"195","author":"Silverman","year":"1999","journal-title":"Pathol Res Pract"},{"key":"2025082707084577000_12.12.e231320.5","doi-asserted-by":"crossref","unstructured":"Yada K , Ishibashi H , Mori H , et al . 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