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The patient underwent surgical resection of the shoulder mass which comprised of SCC (&gt;95%) and adenoid basal cell carcinoma (BCC) as a second component of the tumour. The BCC had identical histology as the metastatic carcinoma in the left axillary lymph node. Therefore, diagnosis was revised as cutaneous collision tumour with metastatic BCC. Six months later following adjuvant radiation therapy, the patient was diagnosed with metastatic BCC in the right lung. Stereotactic body radiation therapy (SBRT) and a selective hedgehog pathway inhibitor vismodegib were given with only limited efficacy. Clinical trial registration number <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"clintrialgov\" xlink:href=\"NCT03132636\">NCT03132636<\/jats:ext-link>.<\/jats:p>","DOI":"10.1136\/bcr-2019-231487","type":"journal-article","created":{"date-parts":[[2019,10,4]],"date-time":"2019-10-04T07:35:12Z","timestamp":1570174512000},"page":"e231487","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Rare basal cell metastasis of a basal-squamous skin collision tumour to the lung and axillary lymph node"],"prefix":"10.1136","volume":"12","clinical-trial-number":[{"clinical-trial-number":"nct03132636","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Rui","family":"Li","sequence":"first","affiliation":[{"name":"Pulmonary and Critical Care, UCLA, Los Angeles, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0628-6930","authenticated-orcid":false,"given":"Gina","family":"Lee","sequence":"additional","affiliation":[{"name":"Pulmonary and Critical Care, UCLA, Los Angeles, California, USA"},{"name":"Pulmonary and Critical Care, Greater Los Angeles Veteran Affairs Medical Center, Los Angeles, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Huang","sequence":"additional","affiliation":[{"name":"Pathology, Greater Los Angeles Veterans Affairs Healthcare System, Los Angeles, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"El-Sherief","sequence":"additional","affiliation":[{"name":"Radiology, UCLA, Los Angeles, California, USA"},{"name":"Radiology, Greater Los Angeles Veterans Affairs Healthcare System, Los Angeles, CA, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,10,3]]},"reference":[{"key":"2025082708230893000_12.10.e231487.1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-199406000-00005"},{"key":"2025082708230893000_12.10.e231487.2","first-page":"28","article-title":"Collision tumor of basal and squamous cell carcinoma of the palm","volume":"12","author":"Lam","year":"2019","journal-title":"J Clin Aesthet Dermatol"},{"key":"2025082708230893000_12.10.e231487.3","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1007\/s00292-019-0622-3","article-title":"[Malignant collision tumor of the skin : Melanoma, squamous cell carcinoma and basal cell carcinoma]","volume":"40","author":"Sterz","year":"2019","journal-title":"Pathologe"},{"key":"2025082708230893000_12.10.e231487.4","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1056\/NEJMra1708701","article-title":"Update on keratinocyte carcinomas","volume":"379","author":"Nehal","year":"2018","journal-title":"N Engl J Med"},{"key":"2025082708230893000_12.10.e231487.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2012.04.030"},{"key":"2025082708230893000_12.10.e231487.6","first-page":"228","article-title":"Basal cell carcinomas - 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