{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T23:42:29Z","timestamp":1784158949761,"version":"3.55.0"},"reference-count":21,"publisher":"BMJ","issue":"12","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,10,30]]},"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:p>\n                  <jats:italic>Sphingomonas paucimobilis<\/jats:italic> is a low-virulence gram-negative bacillus known to cause various ocular infections such as endophthalmitis, panophthalmitis and keratitis that are usually associated with an underlying risk factor such as peri-partum or postpartum phase, cataract surgery, contact lens use, neurotrophic keratopathy or ocular trauma. We report a case of spontaneously occurring perforated corneal ulcer caused by the organism in a young man managed by penetrating keratoplasty. The course was followed by endophthalmitis with graft infection culminating in phthisis bulbi despite aggressive medical and surgical management. Along with reporting this case, we also present a review of literature on ocular infections caused by the same organism.<\/jats:p>","DOI":"10.1136\/bcr-2019-231642","type":"journal-article","created":{"date-parts":[[2019,12,4]],"date-time":"2019-12-04T05:04:25Z","timestamp":1575435865000},"page":"e231642","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Fulminant <i>Sphingomonas paucimobilis<\/i> keratitis: case study and review of literature"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4576-4915","authenticated-orcid":false,"given":"Rinky","family":"Agarwal","sequence":"first","affiliation":[{"name":"Ophthalmology, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meghal","family":"Gagrani","sequence":"additional","affiliation":[{"name":"Ophthalmology, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asmita","family":"Mahajan","sequence":"additional","affiliation":[{"name":"Ophthalmology, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Namrata","family":"Sharma","sequence":"additional","affiliation":[{"name":"Ophthalmology, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2019,12,3]]},"reference":[{"key":"2025082623370399000_12.12.e231642.1","doi-asserted-by":"crossref","first-page":"184","DOI":"10.18295\/2075-0528.2789","article-title":"Bacterial keratitis: perspective on epidemiology, clinico-pathogenesis, diagnosis and treatment","volume":"9","author":"Al-Mujaini","year":"2009","journal-title":"Sultan Qaboos Univ Med J"},{"key":"2025082623370399000_12.12.e231642.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2010.08.007"},{"key":"2025082623370399000_12.12.e231642.3","first-page":"343","article-title":"Comparative study of bacterial status from conjunctival sac of the elder Qiang minority and Han people with dry eye in Sichuan, China","volume":"5","author":"Zhang","year":"2012","journal-title":"Int J Ophthalmol"},{"key":"2025082623370399000_12.12.e231642.4","doi-asserted-by":"crossref","unstructured":"Vinod Kumar B , Hobani YH , Abdulhaq A , et al . 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