{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T12:55:13Z","timestamp":1787921713796,"version":"build-2784847793"},"reference-count":8,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,2,11]]},"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:p>We report two cases of gastric metastases from primary breast cancers. In case 1, a 31-year-old woman with right-sided ductal breast carcinoma presented with nausea, vomiting and frank haematemesis, 8\u2009months after mastectomy and adjuvant chemotherapy. An esophagogastroduodenoscopy (EGD) revealed multiple ulcerated gastric lesions secondary to metastatic adenocarcinoma from primary breast tumour. In case 2, an 84-year-old woman with a history of left lobular carcinoma presented with early satiety, 17 years after initial mastectomy and adjuvant endocrine therapy. An EGD revealed unspecific gastric mucosa with thickened and erythematous folds and biopsies revealed adenocarcinoma from primary breast carcinoma. Our cases demonstrate how gastric metastases have variable, non-specific clinical and endoscopic presentations. Symptoms may include nausea, vomiting, early satiety and gastrointestinal (GI) bleeding. Endoscopic appearance may range from thickened gastric folds to ulcerating lesions. Our cases demonstrate that gastric metastases should be considered in patients with breast cancer history presenting with GI symptoms.<\/jats:p>","DOI":"10.1136\/bcr-2019-231763","type":"journal-article","created":{"date-parts":[[2020,7,7]],"date-time":"2020-07-07T06:02:37Z","timestamp":1594101757000},"page":"e231763","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Gastric metastases from primary breast cancers: rare causes of common gastrointestinal disorders"],"prefix":"10.1136","volume":"13","author":[{"given":"Tiffany","family":"Yuen","sequence":"first","affiliation":[{"name":"Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eddie","family":"Liu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Kohansal","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2020,7,6]]},"reference":[{"key":"2025082707534398000_13.7.e231763.1","doi-asserted-by":"crossref","first-page":"94","DOI":"10.4081\/rt.2016.6305","article-title":"Gastric metastasis of breast cancer: a case series","volume":"8","author":"Dos Santos Fernandes","year":"2016","journal-title":"Rare Tumors"},{"key":"2025082707534398000_13.7.e231763.2","doi-asserted-by":"crossref","first-page":"6219","DOI":"10.3748\/wjg.v12.i38.6219","article-title":"Metastatic breast cancer to the gastrointestinal tract: a case series and review of the literature","volume":"12","author":"Nazareno","year":"2006","journal-title":"World J Gastroenterol"},{"key":"2025082707534398000_13.7.e231763.3","doi-asserted-by":"publisher","DOI":"10.1245\/ASO.2005.03.030"},{"key":"2025082707534398000_13.7.e231763.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2011.04.009"},{"key":"2025082707534398000_13.7.e231763.5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2012\/439023","article-title":"Metastatic breast cancer to the gastrointestinal tract: report of five cases and review of the literature","volume":"2012","author":"Ambroggi","year":"2012","journal-title":"Int J Breast Cancer"},{"key":"2025082707534398000_13.7.e231763.6","doi-asserted-by":"crossref","first-page":"4069","DOI":"10.3892\/ol.2017.6703","article-title":"Metastatic gastric cancer from breast carcinoma: a report of 78 cases","volume":"14","author":"Xu","year":"2017","journal-title":"Oncol Lett"},{"key":"2025082707534398000_13.7.e231763.7","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1007\/s12282-011-0284-3","article-title":"Clinicopathological features of gastric metastasis from breast cancer in three cases","volume":"21","author":"Koike","year":"2014","journal-title":"Breast Cancer"},{"key":"2025082707534398000_13.7.e231763.8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2016\/2085452","article-title":"Breast cancer metastasis to the stomach that was diagnosed after endoscopic submucosal dissection","volume":"2016","author":"Kita","year":"2016","journal-title":"Case Rep Gastrointest Med"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2019-231763","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:53:57Z","timestamp":1756306437000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2019-231763"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":8,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2020,7,6]]},"published-print":{"date-parts":[[2020,7]]}},"alternative-id":["10.1136\/bcr-2019-231763"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2019-231763","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7]]}}}