{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T16:45:34Z","timestamp":1788367534081,"version":"build-2803163510"},"reference-count":16,"publisher":"BMJ","issue":"3","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,1,26]]},"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:p>Herein we report a case of a 67-year-old man with chronic lymphocytic leukaemia who developed acute onset of fever and altered mental status while receiving ibrutinib therapy. He was eventually found to have <jats:italic>Capnocytophaga canimorsus<\/jats:italic> meningitis. Timely diagnosis and appropriate antimicrobial therapy was associated with a favourable outcome. We describe challenges associated with appropriate identification of, and briefly review infections caused by <jats:italic>Capnocytophaga<\/jats:italic> sp. To our knowledge, this is the first case of invasive <jats:italic>C. canimorsus<\/jats:italic> infection in the setting of ibrutinib therapy, and adds to the growing list of serious infections that have been associated with this agent.<\/jats:p>","DOI":"10.1136\/bcr-2019-231825","type":"journal-article","created":{"date-parts":[[2020,3,19]],"date-time":"2020-03-19T05:35:14Z","timestamp":1584596114000},"page":"e231825","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["Unexpected pathogen presenting with purulent meningitis"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6161-7088","authenticated-orcid":false,"given":"Jamie","family":"Bering","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Mayo Clinic, Phoenix, Arizona, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Hartmann","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Mayo Clinic, Phoenix, Arizona, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kara","family":"Asbury","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Mayo Clinic, Phoenix, Arizona, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6391-0349","authenticated-orcid":false,"given":"Holenarasipur R","family":"Vikram","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Mayo Clinic, Phoenix, Arizona, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2020,3,18]]},"reference":[{"key":"2025082703530603000_13.3.e231825.1","doi-asserted-by":"publisher","DOI":"10.1086\/345477"},{"key":"2025082703530603000_13.3.e231825.2","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s40121-019-0233-6","article-title":"Capnocytophaga canimorsus meningitis: diagnosis using polymerase chain reaction testing and systematic review of the literature","volume":"8","author":"Hansen","year":"2019","journal-title":"Infect Dis Ther"},{"key":"2025082703530603000_13.3.e231825.3","doi-asserted-by":"publisher","DOI":"10.1007\/BF00144007"},{"key":"2025082703530603000_13.3.e231825.4","doi-asserted-by":"publisher","DOI":"10.1136\/practneurol-2015-001166"},{"key":"2025082703530603000_13.3.e231825.5","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/23.1.71"},{"key":"2025082703530603000_13.3.e231825.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2014.03.023"},{"key":"2025082703530603000_13.3.e231825.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2007.02.010"},{"key":"2025082703530603000_13.3.e231825.8","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/65.4.564"},{"key":"2025082703530603000_13.3.e231825.9","doi-asserted-by":"publisher","DOI":"10.3201\/eid1202.050783"},{"key":"2025082703530603000_13.3.e231825.10","doi-asserted-by":"publisher","DOI":"10.1086\/322649"},{"key":"2025082703530603000_13.3.e231825.11","doi-asserted-by":"crossref","first-page":"325","DOI":"10.3343\/alm.2014.34.4.325","article-title":"Capnocytophaga sputigena bacteremia in a patient with chronic lymphocytic leukemia","volume":"34","author":"Kim","year":"2014","journal-title":"Ann Lab Med"},{"key":"2025082703530603000_13.3.e231825.12","doi-asserted-by":"publisher","DOI":"10.1086\/425368"},{"key":"2025082703530603000_13.3.e231825.13","unstructured":"Janda JM , Mandell D . 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