{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T12:49:17Z","timestamp":1778503757115,"version":"3.51.4"},"reference-count":18,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,9,19]]},"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:p>Xanthogranulomatous pyelonephritis is associated with obstruction, stones and infection. CT is the mainstay of diagnosis, but appearances can mimic other conditions, including renal cell carcinoma. Nephrectomy is commonly recommended, but conservative treatment with antibiotics has been described after tissue diagnosis. We present a case of xanthogranulomatous pyelonephritis with concomitant renal cell carcinoma, which was an association that was suggested in 1988 and supported by subsequently reported cases. Conservative management of biopsy or cytology proven xanthogranulomatous pyelonephritis is unsafe, as an area of synchronous malignant tumour may be missed: we recommend it only in patients unfit for nephrectomy.<\/jats:p>","DOI":"10.1136\/bcr-2019-232097","type":"journal-article","created":{"date-parts":[[2019,10,5]],"date-time":"2019-10-05T14:55:31Z","timestamp":1570287331000},"page":"e232097","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Xanthogranulomatous pyelonephritis with associated renal cell carcinoma"],"prefix":"10.1136","volume":"12","author":[{"given":"Basil Francis","family":"Moss","sequence":"first","affiliation":[{"name":"Department of Urology, Wirral University Teaching Hospital NHS Foundation Trust, Wirral, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Potter","sequence":"additional","affiliation":[{"name":"Department of Pathology, Wirral University Teaching Hospital NHS Foundation Trust, Wirral, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Cliff","sequence":"additional","affiliation":[{"name":"Department of Urology, Wirral University Teaching Hospital NHS Foundation Trust, Wirral, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manal","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Urology, Wirral University Teaching Hospital NHS Foundation Trust, Wirral, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,10,5]]},"reference":[{"key":"2025082703420123000_12.10.e232097.1","unstructured":"Schlagenhaufer F . Uber epigentumliche Staphylmykosen der Nieven undder pararenalen Bindegewebes. Frankfurt Z Pathol 1916:139\u201348."},{"key":"2025082703420123000_12.10.e232097.2","doi-asserted-by":"crossref","first-page":"671","DOI":"10.5858\/2009-0769-RSR.1","article-title":"Xanthogranulomatous pyelonephritis","volume":"135","author":"Li","year":"2011","journal-title":"Arch Pathol Lab Med"},{"key":"2025082703420123000_12.10.e232097.3","doi-asserted-by":"publisher","DOI":"10.1016\/0090-4295(92)90307-I"},{"key":"2025082703420123000_12.10.e232097.4","first-page":"712","article-title":"Xanthogranulomatous pyelonephritis","volume":"19","author":"\u00c7aliskan","year":"2016","journal-title":"Arch Iran Med"},{"key":"2025082703420123000_12.10.e232097.5","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/S1726-4901(09)70008-5","article-title":"Xanthogranulomatous pyelonephritis successfully treated with antibiotics only","volume":"71","author":"Ho","year":"2008","journal-title":"J Chin Med Assoc"},{"key":"2025082703420123000_12.10.e232097.6","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/S0022-5347(17)61406-X","article-title":"Xanthogranulomatous pyelonephritis: an unusual case","volume":"106","author":"Butnick","year":"1971","journal-title":"J Urol"},{"key":"2025082703420123000_12.10.e232097.7","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1111\/j.1464-410X.1968.tb11847.x","article-title":"Xanthogranulomatous pyelonephritis and perirenal xanthogranuloma","volume":"40","author":"Elliott","year":"1968","journal-title":"Br J Urol"},{"key":"2025082703420123000_12.10.e232097.8","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/0090-4295(84)90148-1","article-title":"Xanthogranulomatous pyelonephritis with associated renal cell carcinoma","volume":"23","author":"Goulding","year":"1984","journal-title":"Urology"},{"key":"2025082703420123000_12.10.e232097.9","first-page":"520","article-title":"Xanthogranulomatous pyelonephritis: a retrospective study of 10 cases and review of the literature","volume":"12","author":"Fallatah","year":"2001","journal-title":"Saudi J Kidney Dis Transpl"},{"key":"2025082703420123000_12.10.e232097.10","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/S0272-6386(12)80704-9","article-title":"Bilateral xanthogranulomatous pyelonephritis involving native kidneys in a renal transplant recipient: association with renal cell carcinoma and amyloidosis","volume":"20","author":"Akhtar","year":"1992","journal-title":"Am J Kidney Dis"},{"key":"2025082703420123000_12.10.e232097.11","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1159\/000463873","article-title":"Xanthogranulomatous pyelonephritis associated with renal cell carcinoma. Report on two cases and review of the literature","volume":"18","author":"Papadopoulos","year":"1990","journal-title":"Eur Urol"},{"key":"2025082703420123000_12.10.e232097.12","doi-asserted-by":"publisher","DOI":"10.1016\/0090-4295(73)90282-3"},{"key":"2025082703420123000_12.10.e232097.13","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1159\/000463515","article-title":"Association of xanthogranulomatous pyelonephritis with small renal cell carcinoma. Case report and review of the literature","volume":"10","author":"Piscioli","year":"1984","journal-title":"Eur Urol"},{"key":"2025082703420123000_12.10.e232097.14","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0022-5347(17)55325-2","article-title":"Xanthogranulomatous pyelonephritis associated with renal carcinoma","volume":"124","author":"Schoborg","year":"1980","journal-title":"J Urol"},{"key":"2025082703420123000_12.10.e232097.15","doi-asserted-by":"crossref","first-page":"193","DOI":"10.3109\/00365598009179560","article-title":"Xanthogranulomatous pyelonephritis","volume":"14","author":"Lorentzen","year":"1980","journal-title":"Scand J Urol Nephrol"},{"key":"2025082703420123000_12.10.e232097.16","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/0149-936X(87)90100-7","article-title":"Coexistent xanthogranulomatous pyelonephritis and renal cell carcinoma","volume":"11","author":"Radin","year":"1987","journal-title":"J Comput Tomogr"},{"key":"2025082703420123000_12.10.e232097.17","first-page":"608","article-title":"[Association of xanthogranulomatous pyelonephritis and renal cancer]","volume":"40","author":"Prati","year":"1987","journal-title":"Arch Esp Urol"},{"key":"2025082703420123000_12.10.e232097.18","first-page":"275","article-title":"Xanthogranulomatous pyelonephritis. A reappraisal and immunohistochemical study","volume":"112","author":"Antonakopoulos","year":"1988","journal-title":"Arch Pathol Lab Med"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2019-232097","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:42:10Z","timestamp":1756291330000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2019-232097"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":18,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2019,10,5]]},"published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1136\/bcr-2019-232097"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2019-232097","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10]]}}}