{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T12:20:24Z","timestamp":1763727624433,"version":"3.44.0"},"reference-count":15,"publisher":"BMJ","issue":"11","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,10,16]]},"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:p>We present an atypical presentation of Rosai-Dorfman disease (RDD). Due to its overlap with IgG4-related disease (IgG4-RD), this case proved to be a diagnostic dilemma. Our case is an example of the importance of having a broad-based differential and, ultimately, an in-depth histopathological review. Our patient presented with a constellation of symptoms suggestive of an underlying malignancy. He was provisionally diagnosed with peritoneal carcinomatosis of an unknown primary. His initial presentation triggered a series of investigations, surgery and biopsies. Omental biopsy specimens were suggestive of IgG4-RD. Despite appropriate treatment for IgG4-RD, his disease progressed, specifically in the lungs. Pleural biopsies were then collected and assessed alongside the omental biopsies. On review and reassessment, the patient was formally diagnosed with RDD.<\/jats:p>","DOI":"10.1136\/bcr-2019-232165","type":"journal-article","created":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T05:48:07Z","timestamp":1575265687000},"page":"e232165","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Histiocytosis masquerading in the mesentery and pleura"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0341-8472","authenticated-orcid":false,"given":"Nina","family":"Dhillon","sequence":"first","affiliation":[{"name":"University of Queensland, Herston, Queensland, Australia"},{"name":"Department of Pathology, Vancouver General Hospital, Vancouver, British Columbia, Canada"},{"name":"Artus Health Centre, Vancouver, British Columbia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Skinnider","sequence":"additional","affiliation":[{"name":"Department of Pathology, Vancouver General Hospital, Vancouver, British Columbia, Canada"},{"name":"Department of Pathology and Laboratory Medicine, The University of British Columbia Faculty of Medicine, Vancouver, British Columbia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saman","family":"Darabian","sequence":"additional","affiliation":[{"name":"Sciences, The University of British Columbia, Vancouver, British Columbia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mollie","family":"Carruthers","sequence":"additional","affiliation":[{"name":"Rheumatology, The University of British Columbia, Vancouver, British Columbia, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,12,1]]},"reference":[{"key":"2025082723375130000_12.11.e232165.1","first-page":"19","article-title":"Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): review of the entity","volume":"7","author":"Foucar","year":"1990","journal-title":"Semin Diagn Pathol"},{"key":"2025082723375130000_12.11.e232165.2","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.5858\/2007-131-1117-MESHWM","article-title":"Multifocal, extranodal sinus histiocytosis with massive lymphadenopathy: an overview","volume":"131","author":"Gaitonde","year":"2007","journal-title":"Arch Pathol Lab Med"},{"key":"2025082723375130000_12.11.e232165.3","doi-asserted-by":"crossref","unstructured":"Rajasekharan C , Ratheesh NS , Nandinidevi R , et al . 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