{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T08:40:04Z","timestamp":1756370404984,"version":"3.44.0"},"reference-count":11,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,5,14]]},"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:p>An 83-year-old woman with a long-standing history of both invasive and vulval extramammary Paget\u2019s disease (EMPD) was referred to a tertiary gynaecological oncology service for suspicion of contiguous extension to the vagina and cervix. Vaginal biopsies confirmed EMPD; however, a loop excision of the cervix demonstrated invasive adenocarcinoma arising from Paget\u2019s disease. The patient subsequently underwent laparoscopic radical hysterectomy, bilateral salpingo-oophorectomy and radical upper vaginectomy, confirming FIGO stage 1B1 cervical adenocarcinoma. She was recommended but declined to have adjuvant pelvic external beam radiotherapy. To our knowledge this is the second case of invasive cervical adenocarcinoma arising from vulval Paget\u2019s disease in the literature.<\/jats:p>","DOI":"10.1136\/bcr-2019-232424","type":"journal-article","created":{"date-parts":[[2020,6,12]],"date-time":"2020-06-12T05:57:01Z","timestamp":1591941421000},"page":"e232424","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Invasive cervical adenocarcinoma arising from extension of recurrent vulval Paget\u2019s disease"],"prefix":"10.1136","volume":"13","author":[{"given":"Liesel Elisabeth","family":"Hardy","sequence":"first","affiliation":[{"name":"Gynaecological Oncology, King Edward Memorial Hospital for Women, Perth, Western Australia, Australia"},{"name":"Pathology, Queen Elizabeth II Medical Centre, Nedlands, Western Australia, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lachlan","family":"Baxter","sequence":"additional","affiliation":[{"name":"Gynaecological Oncology, King Edward Memorial Hospital for Women, Perth, Western Australia, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"King","family":"Wan","sequence":"additional","affiliation":[{"name":"Gynaecological Oncology, King Edward Memorial Hospital for Women, Perth, Western Australia, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chloe","family":"Ayres","sequence":"additional","affiliation":[{"name":"Gynaecological Oncology, King Edward Memorial Hospital for Women, Perth, Western Australia, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,6,11]]},"reference":[{"key":"2025082801212099000_13.6.e232424.1","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2018.00038","article-title":"Metastatic extramammary Paget's disease: pathogenesis and novel therapeutic approach","volume":"16","author":"Fukuda","year":"2018","journal-title":"Front Oncol"},{"key":"2025082801212099000_13.6.e232424.2","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1136\/jcp.52.7.538","article-title":"Extension of extramammary Paget disease of the vulva to the cervix","volume":"52","author":"Lloyd","year":"1999","journal-title":"J Clin Pathol"},{"key":"2025082801212099000_13.6.e232424.3","unstructured":"McDaniel B , Crane JS . 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